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A comprehensive AI-driven analysis of large-scale omic datasets reveals novel dual-purpose targets for the treatment of cancer and aging.
Pun FW, Leung GHD, Leung HW, Rice J, Schmauck-Medina T, Lautrup S, Long X, Liu BHM, Wong CW, Ozerov IV, Aliper A, Ren F, Rosenberg AJ, Agrawal N, Izumchenko E, Fang EF, Zhavoronkov A. Pun FW, et al. Among authors: lautrup s. Aging Cell. 2023 Dec;22(12):e14017. doi: 10.1111/acel.14017. Epub 2023 Oct 27. Aging Cell. 2023. PMID: 37888486 Free PMC article.
NAD+ in Brain Aging and Neurodegenerative Disorders.
Lautrup S, Sinclair DA, Mattson MP, Fang EF. Lautrup S, et al. Cell Metab. 2019 Oct 1;30(4):630-655. doi: 10.1016/j.cmet.2019.09.001. Cell Metab. 2019. PMID: 31577933 Free PMC article. Review.
Enhanced brain mitophagy slows systemic aging.
Lautrup S, Fang EF. Lautrup S, et al. Nat Aging. 2022 Jun;2(6):463-464. doi: 10.1038/s43587-022-00226-8. Nat Aging. 2022. PMID: 37118448 No abstract available.
Roles of NAD+ in Health and Aging.
Lautrup S, Hou Y, Fang EF, Bohr VA. Lautrup S, et al. Cold Spring Harb Perspect Med. 2024 Jan 2;14(1):a041193. doi: 10.1101/cshperspect.a041193. Cold Spring Harb Perspect Med. 2024. PMID: 37848251 Review.
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary.
Schmauck-Medina T, Molière A, Lautrup S, Zhang J, Chlopicki S, Madsen HB, Cao S, Soendenbroe C, Mansell E, Vestergaard MB, Li Z, Shiloh Y, Opresko PL, Egly JM, Kirkwood T, Verdin E, Bohr VA, Cox LS, Stevnsner T, Rasmussen LJ, Fang EF. Schmauck-Medina T, et al. Among authors: lautrup s. Aging (Albany NY). 2022 Aug 29;14(16):6829-6839. doi: 10.18632/aging.204248. Epub 2022 Aug 29. Aging (Albany NY). 2022. PMID: 36040386 Free PMC article.
Mitophagy in neurodegeneration and aging.
Fivenson EM, Lautrup S, Sun N, Scheibye-Knudsen M, Stevnsner T, Nilsen H, Bohr VA, Fang EF. Fivenson EM, et al. Among authors: lautrup s. Neurochem Int. 2017 Oct;109:202-209. doi: 10.1016/j.neuint.2017.02.007. Epub 2017 Feb 21. Neurochem Int. 2017. PMID: 28235551 Free PMC article. Review.
NAD+ in Aging: Molecular Mechanisms and Translational Implications.
Fang EF, Lautrup S, Hou Y, Demarest TG, Croteau DL, Mattson MP, Bohr VA. Fang EF, et al. Among authors: lautrup s. Trends Mol Med. 2017 Oct;23(10):899-916. doi: 10.1016/j.molmed.2017.08.001. Epub 2017 Sep 9. Trends Mol Med. 2017. PMID: 28899755 Free PMC article. Review.
29 results