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Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma.
VanSant-Webb C, Low HK, Kuramoto J, Stanley CE, Qiang H, Su A, Ross AN, Cooper CG, Cox JE, Summers SA, Evason KJ, Ducker GS. VanSant-Webb C, et al. Among authors: cox je. bioRxiv [Preprint]. 2023 Oct 16:2023.10.12.562134. doi: 10.1101/2023.10.12.562134. bioRxiv. 2023. Update in: Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Aug;1869(6):159514. doi: 10.1016/j.bbalip.2024.159514 PMID: 37904922 Free PMC article. Updated. Preprint.
Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Among authors: cox je. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency.
Verkerke ARP, Ferrara PJ, Lin CT, Johnson JM, Ryan TE, Maschek JA, Eshima H, Paran CW, Laing BT, Siripoksup P, Tippetts TS, Wentzler EJ, Huang H, Spangenburg EE, Brault JJ, Villanueva CJ, Summers SA, Holland WL, Cox JE, Vance DE, Neufer PD, Funai K. Verkerke ARP, et al. Among authors: cox je. Nat Metab. 2019 Sep;1(9):876-885. doi: 10.1038/s42255-019-0111-2. Epub 2019 Sep 16. Nat Metab. 2019. PMID: 32405618 Free PMC article.
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis.
Panic V, Pearson S, Banks J, Tippetts TS, Velasco-Silva JN, Lee S, Simcox J, Geoghegan G, Bensard CL, van Ry T, Holland WL, Summers SA, Cox J, Ducker GS, Rutter J, Villanueva CJ. Panic V, et al. Elife. 2020 Aug 14;9:e52558. doi: 10.7554/eLife.52558. Elife. 2020. PMID: 32795388 Free PMC article.
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG. Cluntun AA, et al. Among authors: cox je. Cell Metab. 2021 Mar 2;33(3):629-648.e10. doi: 10.1016/j.cmet.2020.12.003. Epub 2020 Dec 16. Cell Metab. 2021. PMID: 33333007 Free PMC article.
263 results