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Chronic GCPII (glutamate-carboxypeptidase-II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaques.
Bathla S, Datta D, Liang F, Barthelemy N, Wiseman R, Slusher BS, Asher J, Zeiss C, Ekanayake-Alper D, Holden D, Terwilliger G, Duque A, Arellano J, van Dyck C, Bateman RJ, Xie Z, Nairn AC, Arnsten AFT. Bathla S, et al. Among authors: duque a. Alzheimers Dement (N Y). 2023 Oct 31;9(4):e12431. doi: 10.1002/trc2.12431. eCollection 2023 Oct-Dec. Alzheimers Dement (N Y). 2023. PMID: 37915375 Free PMC article.
Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels.
El-Hassar L, Simen AA, Duque A, Patel KD, Kaczmarek LK, Arnsten AF, Yeckel MF. El-Hassar L, et al. Among authors: duque a. Biol Psychiatry. 2014 Sep 15;76(6):476-85. doi: 10.1016/j.biopsych.2013.12.019. Epub 2014 Jan 20. Biol Psychiatry. 2014. PMID: 24560582 Free PMC article.
311 results