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Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent.
Subramanian R, Tang J, Zheng J, Lu B, Wang K, Yant SR, Stepan GJ, Mulato A, Yu H, Schroeder S, Shaik N, Singh R, Wolckenhauer S, Chester A, Tse WC, Chiu A, Rhee M, Cihlar T, Rowe W, Smith BJ. Subramanian R, et al. Among authors: chester a. Mol Pharm. 2023 Dec 4;20(12):6213-6225. doi: 10.1021/acs.molpharmaceut.3c00626. Epub 2023 Nov 2. Mol Pharm. 2023. PMID: 37917742 Free PMC article.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Link JO, Rhee MS, Tse WC, Zheng J, Somoza JR, Rowe W, Begley R, Chiu A, Mulato A, Hansen D, Singer E, Tsai LK, Bam RA, Chou CH, Canales E, Brizgys G, Zhang JR, Li J, Graupe M, Morganelli P, Liu Q, Wu Q, Halcomb RL, Saito RD, Schroeder SD, Lazerwith SE, Bondy S, Jin D, Hung M, Novikov N, Liu X, Villaseñor AG, Cannizzaro CE, Hu EY, Anderson RL, Appleby TC, Lu B, Mwangi J, Liclican A, Niedziela-Majka A, Papalia GA, Wong MH, Leavitt SA, Xu Y, Koditek D, Stepan GJ, Yu H, Pagratis N, Clancy S, Ahmadyar S, Cai TZ, Sellers S, Wolckenhauer SA, Ling J, Callebaut C, Margot N, Ram RR, Liu YP, Hyland R, Sinclair GI, Ruane PJ, Crofoot GE, McDonald CK, Brainard DM, Lad L, Swaminathan S, Sundquist WI, Sakowicz R, Chester AE, Lee WE, Daar ES, Yant SR, Cihlar T. Link JO, et al. Among authors: chester ae. Nature. 2020 Aug;584(7822):614-618. doi: 10.1038/s41586-020-2443-1. Epub 2020 Jul 1. Nature. 2020. PMID: 32612233 Free PMC article. Clinical Trial.
Proton Shell Gaps in N=28 Nuclei from the First Complete Spectroscopy Study with FRIB Decay Station Initiator.
Cox I, Xu ZY, Grzywacz R, Ong WJ, Rasco BC, Kitamura N, Hoskins D, Neupane S, Ruland TJ, Allmond JM, King TT, Lubna RS, Rykaczewski KP, Schatz H, Sherrill BM, Tarasov OB, Ayangeakaa AD, Berg HC, Bleuel DL, Cerizza G, Christie J, Chester A, Davis J, Dembski C, Doetsch AA, Duarte JG, Estrade A, Fijałkowska A, Gray TJ, Good EC, Haak K, Hanai S, Harke JT, Harris C, Hermansen K, Hoff DEM, Jain R, Karny M, Kolos K, Laminack A, Liddick SN, Longfellow B, Lyons S, Madurga M, Mogannam MJ, Nowicki A, Ogunbeku TH, Owens-Fryar G, Rajabali MM, Richard AL, Ronning EK, Rose GE, Siegl K, Singh M, Spyrou A, Sweet A, Tsantiri A, Walters WB, Yokoyama R. Cox I, et al. Among authors: chester a. Phys Rev Lett. 2024 Apr 12;132(15):152503. doi: 10.1103/PhysRevLett.132.152503. Phys Rev Lett. 2024. PMID: 38682970
344 results