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The Set1 Histone H3K4 Methyltransferase Contributes to Azole Susceptibility in a Species-Specific Manner by Differentially Altering the Expression of Drug Efflux Pumps and the Ergosterol Gene Pathway.
Baker KM, Hoda S, Saha D, Gregor JB, Georgescu L, Serratore ND, Zhang Y, Cheng L, Lanman NA, Briggs SD. Baker KM, et al. Among authors: saha d. Antimicrob Agents Chemother. 2022 May 17;66(5):e0225021. doi: 10.1128/aac.02250-21. Epub 2022 Apr 26. Antimicrob Agents Chemother. 2022. PMID: 35471041 Free PMC article.
Candida glabrata maintains two Hap1 homologs, Zcf27 and Zcf4, for distinct roles in ergosterol gene regulation to mediate sterol homeostasis under azole and hypoxic conditions.
Saha D, Gregor JB, Hoda S, Eastman KE, Navarrete M, Wisecaver JH, Briggs SD. Saha D, et al. bioRxiv [Preprint]. 2024 Jun 24:2024.06.20.599910. doi: 10.1101/2024.06.20.599910. bioRxiv. 2024. Update in: mSphere. 2024 Nov 21;9(11):e0052424. doi: 10.1128/msphere.00524-24 PMID: 38979343 Free PMC article. Updated. Preprint.
904 results