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Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer.
Boelaars K, Goossens-Kruijssen L, Wang D, de Winde CM, Rodriguez E, Lindijer D, Springer B, van der Haar Àvila I, de Haas A, Wehry L, Boon L, Mebius RE, van Montfoort N, Wuhrer M, den Haan JMM, van Vliet SJ, van Kooyk Y. Boelaars K, et al. Among authors: boon l. J Immunother Cancer. 2023 Nov;11(11):e007805. doi: 10.1136/jitc-2023-007805. J Immunother Cancer. 2023. PMID: 37940346 Free PMC article.
Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice.
Singh A, Mommers-Elshof ETAM, Vijver SV, Jansen JHM, Gonder S, Lebbink RJ, Bihan D, Farndale RW, Boon L, Langermann S, Leusen JHW, Flies D, Meyaard L, Pascoal Ramos MI. Singh A, et al. Among authors: boon l. Cancer Immunol Immunother. 2024 Jan 18;73(1):16. doi: 10.1007/s00262-023-03600-6. Cancer Immunol Immunother. 2024. PMID: 38236251 Free PMC article.
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells.
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, Felsberg J, Sabel MC, Rapp M, Knobbe-Thomsen C, Liu P, Zhao L, Kepp O, Boon L, Tejpar S, Borst J, Kroemer G, Schlenner S, De Vleeschouwer S, Sorg RV, Garg AD. Sprooten J, et al. Among authors: boon l. Cell Rep Med. 2024 Jan 16;5(1):101377. doi: 10.1016/j.xcrm.2023.101377. Cell Rep Med. 2024. PMID: 38232703 Free PMC article.
Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
Paudel SN, Hutzen BJ, Miller KE, Garfinkle EAR, Chen CY, Wang PY, Glaspell AM, Currier MA, Ringwalt EM, Boon L, Mardis ER, Cairo MS, Ratner N, Dodd RD, Cassady KA, Cripe TP. Paudel SN, et al. Among authors: boon l. Front Immunol. 2024 Jun 25;15:1384623. doi: 10.3389/fimmu.2024.1384623. eCollection 2024. Front Immunol. 2024. PMID: 39044819 Free PMC article.
PD-L1 blockade immunotherapy rewires cancer-induced emergency myelopoiesis.
Boumpas A, Papaioannou AS, Bousounis P, Grigoriou M, Bergo V, Papafragkos I, Tasis A, Iskas M, Boon L, Makridakis M, Vlachou A, Gavriilaki E, Hatzioannou A, Mitroulis I, Trompouki E, Verginis P. Boumpas A, et al. Among authors: boon l. Front Immunol. 2024 Oct 11;15:1386838. doi: 10.3389/fimmu.2024.1386838. eCollection 2024. Front Immunol. 2024. PMID: 39464894 Free PMC article.
Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes.
Kidman J, Zemek RM, Sidhom JW, Correa D, Principe N, Sheikh F, Fear VS, Forbes CA, Chopra A, Boon L, Zaitouny A, de Jong E, Holt RA, Jones M, Millward MJ, Lassmann T, Forrest ARR, Nowak AK, Watson M, Lake RA, Lesterhuis WJ, Chee J. Kidman J, et al. Among authors: boon l. Oncoimmunology. 2024 Apr 26;13(1):2345859. doi: 10.1080/2162402X.2024.2345859. eCollection 2024. Oncoimmunology. 2024. PMID: 38686178 Free PMC article.
Immunological synapse formation between T regulatory cells and cancer-associated fibroblasts promotes tumour development.
Varveri A, Papadopoulou M, Papadovasilakis Z, Compeer EB, Legaki AI, Delis A, Damaskou V, Boon L, Papadogiorgaki S, Samiotaki M, Foukas PG, Eliopoulos AG, Hatzioannou A, Alissafi T, Dustin ML, Verginis P. Varveri A, et al. Among authors: boon l. Nat Commun. 2024 Jun 11;15(1):4988. doi: 10.1038/s41467-024-49282-1. Nat Commun. 2024. PMID: 38862534 Free PMC article.
604 results