Kim M - Search Results

1

Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility.

Tan K, Chen J, Kaku Y, Wang Y, Donius L, Khan RA, Li X, Richter H, Seaman MS, Walz T, Hwang W, Reinherz EL, Kim M. Tan K, et al. Among authors: kim m. Nat Commun. 2023 Nov 8;14(1):7218. doi: 10.1038/s41467-023-42097-6. Nat Commun. 2023. PMID: 37940661 Free PMC article.

2

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack.

Yang S, Hiotis G, Wang Y, Chen J, Wang JH, Kim M, Reinherz EL, Walz T. Yang S, et al. Among authors: kim m. Nat Commun. 2022 Oct 27;13(1):6393. doi: 10.1038/s41467-022-34008-y. Nat Commun. 2022. PMID: 36302771 Free PMC article.

3

Comparison of HIV Type 1 ADA gp120 monomers versus gp140 trimers as immunogens for the induction of neutralizing antibodies.

Kim M, Qiao ZS, Montefiori DC, Haynes BF, Reinherz EL, Liao HX. Kim M, et al. AIDS Res Hum Retroviruses. 2005 Jan;21(1):58-67. doi: 10.1089/aid.2005.21.58. AIDS Res Hum Retroviruses. 2005. PMID: 15665645

4

Design, expression, and immunogenicity of a soluble HIV trimeric envelope fragment adopting a prefusion gp41 configuration.

Qiao ZS, Kim M, Reinhold B, Montefiori D, Wang JH, Reinherz EL. Qiao ZS, et al. Among authors: kim m. J Biol Chem. 2005 Jun 17;280(24):23138-46. doi: 10.1074/jbc.M414515200. Epub 2005 Apr 15. J Biol Chem. 2005. PMID: 15833740 Free article.

5

Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion state.

Kim M, Qiao Z, Yu J, Montefiori D, Reinherz EL. Kim M, et al. Vaccine. 2007 Jun 28;25(27):5102-14. doi: 10.1016/j.vaccine.2006.09.071. Epub 2006 Oct 9. Vaccine. 2007. PMID: 17055621 Free PMC article.

6

HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane.

Sun ZY, Oh KJ, Kim M, Yu J, Brusic V, Song L, Qiao Z, Wang JH, Wagner G, Reinherz EL. Sun ZY, et al. Among authors: kim m. Immunity. 2008 Jan;28(1):52-63. doi: 10.1016/j.immuni.2007.11.018. Immunity. 2008. PMID: 18191596 Free article.

7

Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface.

Song L, Sun ZY, Coleman KE, Zwick MB, Gach JS, Wang JH, Reinherz EL, Wagner G, Kim M. Song L, et al. Among authors: kim m. Proc Natl Acad Sci U S A. 2009 Jun 2;106(22):9057-62. doi: 10.1073/pnas.0901474106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458040 Free PMC article.

8

Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization.

Kim M, Sun ZY, Rand KD, Shi X, Song L, Cheng Y, Fahmy AF, Majumdar S, Ofek G, Yang Y, Kwong PD, Wang JH, Engen JR, Wagner G, Reinherz EL. Kim M, et al. Nat Struct Mol Biol. 2011 Oct 16;18(11):1235-43. doi: 10.1038/nsmb.2154. Nat Struct Mol Biol. 2011. PMID: 22002224 Free PMC article.

9

Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry.

Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Kim M, et al. J Biol Chem. 2013 Nov 1;288(44):31888-901. doi: 10.1074/jbc.M113.494609. Epub 2013 Sep 18. J Biol Chem. 2013. PMID: 24047898 Free PMC article.

10

Disruption of helix-capping residues 671 and 674 reveals a role in HIV-1 entry for a specialized hinge segment of the membrane proximal external region of gp41.

Sun ZY, Cheng Y, Kim M, Song L, Choi J, Kudahl UJ, Brusic V, Chowdhury B, Yu L, Seaman MS, Bellot G, Shih WM, Wagner G, Reinherz EL. Sun ZY, et al. Among authors: kim m. J Mol Biol. 2014 Mar 6;426(5):1095-108. doi: 10.1016/j.jmb.2013.09.030. Epub 2013 Sep 26. J Mol Biol. 2014. PMID: 24075869 Free PMC article.

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