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CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: taylor n. Nat Immunol. 2023 Dec;24(12):2121-2134. doi: 10.1038/s41590-023-01663-2. Epub 2023 Nov 9. Nat Immunol. 2023. PMID: 37945821 Free PMC article.
CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.
Shalabi H, Qin H, Su A, Yates B, Wolters PL, Steinberg SM, Ligon JA, Silbert S, DéDé K, Benzaoui M, Goldberg S, Achar S, Schneider D, Shahani SA, Little L, Foley T, Molina JC, Panch S, Mackall CL, Lee DW, Chien CD, Pouzolles M, Ahlman M, Yuan CM, Wang HW, Wang Y, Inglefield J, Toledo-Tamula MA, Martin S, Highfill SL, Altan-Bonnet G, Stroncek D, Fry TJ, Taylor N, Shah NN. Shalabi H, et al. Among authors: taylor n. Blood. 2022 Aug 4;140(5):451-463. doi: 10.1182/blood.2022015795. Blood. 2022. PMID: 35605184 Free PMC article. Clinical Trial.
Apoptotic contraction drives target cell release by cytotoxic T cells.
Sanchez EE, Tello-Lafoz M, Guo AJ, de Jesus M, Elbanna YA, Winer BY, Budhu S, Chan E, Rosiek E, Kondo T, DuSold J, Taylor N, Altan-Bonnet G, Olson MF, Huse M. Sanchez EE, et al. Among authors: taylor n. Nat Immunol. 2023 Sep;24(9):1434-1442. doi: 10.1038/s41590-023-01572-4. Epub 2023 Jul 27. Nat Immunol. 2023. PMID: 37500886 Free PMC article.
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides.
Gaud G, Achar S, Bourassa FXP, Davies J, Hatzihristidis T, Choi S, Kondo T, Gossa S, Lee J, Juneau P, Taylor N, Hinrichs CS, McGavern DB, François P, Altan-Bonnet G, Love PE. Gaud G, et al. Among authors: taylor n. Nat Immunol. 2024 Mar;25(3):579. doi: 10.1038/s41590-023-01725-5. Nat Immunol. 2024. PMID: 38057618 No abstract available.
Generation of antitumor chimeric antigen receptors incorporating T cell signaling motifs.
Balagopalan L, Moreno T, Qin H, Angeles BC, Kondo T, Yi J, McIntire KM, Alvinez N, Pallikkuth S, Lee ME, Yamane H, Tran AD, Youkharibache P, Cachau RE, Taylor N, Samelson LE. Balagopalan L, et al. Among authors: taylor n. Sci Signal. 2024 Jul 23;17(846):eadp8569. doi: 10.1126/scisignal.adp8569. Epub 2024 Jul 23. Sci Signal. 2024. PMID: 39042728 Free PMC article.
Women in immunology: 2020 and beyond.
Pierce SK, Schwartzberg PL, Shah NN, Taylor N. Pierce SK, et al. Among authors: taylor n. Nat Immunol. 2020 Mar;21(3):254-258. doi: 10.1038/s41590-020-0618-4. Epub 2020 Feb 24. Nat Immunol. 2020. PMID: 32094649 Free PMC article. Review.
Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients.
Ishii K, Pouzolles M, Chien CD, Erwin-Cohen RA, Kohler ME, Qin H, Lei H, Kuhn S, Ombrello AK, Dulau-Florea A, Eckhaus MA, Shalabi H, Yates B, Lichtenstein DA, Zimmermann VS, Kondo T, Shern JF, Young HA, Taylor N, Shah NN, Fry TJ. Ishii K, et al. Among authors: taylor n. J Clin Invest. 2020 Oct 1;130(10):5425-5443. doi: 10.1172/JCI130059. J Clin Invest. 2020. PMID: 32925169 Free PMC article.
2,721 results