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Page 1
Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.
Nakamura T, Mishima E, Yamada N, Mourão ASD, Trümbach D, Doll S, Wanninger J, Lytton E, Sennhenn P, Nishida Xavier da Silva T, Angeli JPF, Sattler M, Proneth B, Conrad M. Nakamura T, et al. Among authors: trumbach d. Nat Struct Mol Biol. 2023 Nov;30(11):1806-1815. doi: 10.1038/s41594-023-01136-y. Epub 2023 Nov 13. Nat Struct Mol Biol. 2023. PMID: 37957306 Free PMC article.
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. Doll S, et al. Among authors: trumbach d. Nat Chem Biol. 2017 Jan;13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14. Nat Chem Biol. 2017. PMID: 27842070 Free PMC article.
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
Schmidt S, Luecken MD, Trümbach D, Hembach S, Niedermeier KM, Wenck N, Pflügler K, Stautner C, Böttcher A, Lickert H, Ramirez-Suastegui C, Ahmad R, Ziller MJ, Fitzgerald JC, Ruf V, van de Berg WDJ, Jonker AJ, Gasser T, Winner B, Winkler J, Vogt Weisenhorn DM, Giesert F, Theis FJ, Wurst W. Schmidt S, et al. Among authors: trumbach d. Nat Commun. 2022 Aug 16;13(1):4819. doi: 10.1038/s41467-022-32229-9. Nat Commun. 2022. PMID: 35974013 Free PMC article.
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
Schmidt S, Stautner C, Vu DT, Heinz A, Regensburger M, Karayel O, Trümbach D, Artati A, Kaltenhäuser S, Nassef MZ, Hembach S, Steinert L, Winner B, Jürgen W, Jastroch M, Luecken MD, Theis FJ, Westmeyer GG, Adamski J, Mann M, Hiller K, Giesert F, Vogt Weisenhorn DM, Wurst W. Schmidt S, et al. Among authors: trumbach d. Nat Commun. 2023 Nov 23;14(1):7674. doi: 10.1038/s41467-023-42862-7. Nat Commun. 2023. PMID: 37996418 Free PMC article.
Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.
Nouri P, Götz S, Rauser B, Irmler M, Peng C, Trümbach D, Kempny C, Lechermeier CG, Bryniok A, Dlugos A, Euchner E, Beckers J, Brodski C, Klümper C, Wurst W, Prakash N. Nouri P, et al. Among authors: trumbach d. Front Cell Dev Biol. 2020 Oct 26;8:587778. doi: 10.3389/fcell.2020.587778. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33195246 Free PMC article.
Pitchfork regulates primary cilia disassembly and left-right asymmetry.
Kinzel D, Boldt K, Davis EE, Burtscher I, Trümbach D, Diplas B, Attié-Bitach T, Wurst W, Katsanis N, Ueffing M, Lickert H. Kinzel D, et al. Among authors: trumbach d. Dev Cell. 2010 Jul 20;19(1):66-77. doi: 10.1016/j.devcel.2010.06.005. Dev Cell. 2010. PMID: 20643351 Free PMC article.
43 results