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Treatment with recombinant Sirt1 rewires the cardiac lipidome and rescues diabetes-related metabolic cardiomyopathy.
Costantino S, Mengozzi A, Velagapudi S, Mohammed SA, Gorica E, Akhmedov A, Mongelli A, Pugliese NR, Masi S, Virdis A, Hülsmeier A, Matter CM, Hornemann T, Melina G, Ruschitzka F, Luscher TF, Paneni F. Costantino S, et al. Among authors: velagapudi s. Cardiovasc Diabetol. 2023 Nov 13;22(1):312. doi: 10.1186/s12933-023-02057-2. Cardiovasc Diabetol. 2023. PMID: 37957697 Free PMC article.
Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.
Oppi S, Nusser-Stein S, Blyszczuk P, Wang X, Jomard A, Marzolla V, Yang K, Velagapudi S, Ward LJ, Yuan XM, Geiger MA, Guillaumon AT, Othman A, Hornemann T, Rancic Z, Ryu D, Oosterveer MH, Osto E, Lüscher TF, Stein S. Oppi S, et al. Among authors: velagapudi s. Eur Heart J. 2020 Mar 1;41(9):995-1005. doi: 10.1093/eurheartj/ehz667. Eur Heart J. 2020. PMID: 31529020
Inhibition of de novo ceramide synthesis by sirtuin-1 improves beta-cell function and glucose metabolism in type 2 diabetes.
Velagapudi S, Karsai G, Karsai M, Mohammed SA, Montecucco F, Liberale L, Lee H, Carbone F, Adami GF, Yang K, Crucet M, Stein S, Paneni F, Lapikova-Bryhinska T, Jang HD, Kraler S, Vdovenko D, Züllig RA, Camici GG, Kim HS, Laaksonen R, Gerber PA, Hornemann T, Akhmedov A, Lüscher TF. Velagapudi S, et al. Cardiovasc Res. 2024 Sep 21;120(11):1265-1278. doi: 10.1093/cvr/cvae100. Cardiovasc Res. 2024. PMID: 38739545
Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein.
Velagapudi S, Rohrer L, Poti F, Feuerborn R, Perisa D, Wang D, Panteloglou G, Potapenko A, Yalcinkaya M, Hülsmeier AJ, Hesse B, Lukasz A, Liu M, Parks JS, Christoffersen C, Stoffel M, Simoni M, Nofer JR, von Eckardstein A. Velagapudi S, et al. Arterioscler Thromb Vasc Biol. 2021 Oct;41(10):e468-e479. doi: 10.1161/ATVBAHA.121.316725. Epub 2021 Aug 19. Arterioscler Thromb Vasc Biol. 2021. PMID: 34407633 Free PMC article.
Endocytosis of lipoproteins.
Zanoni P, Velagapudi S, Yalcinkaya M, Rohrer L, von Eckardstein A. Zanoni P, et al. Among authors: velagapudi s. Atherosclerosis. 2018 Aug;275:273-295. doi: 10.1016/j.atherosclerosis.2018.06.881. Epub 2018 Jun 23. Atherosclerosis. 2018. PMID: 29980055 Review.
69 results