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Page 1
3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex.
Vue Z, Garza-Lopez E, Neikirk K, Katti P, Vang L, Beasley H, Shao J, Marshall AG, Crabtree A, Murphy AC, Jenkins BC, Prasad P, Evans C, Taylor B, Mungai M, Killion M, Stephens D, Christensen TA, Lam J, Rodriguez B, Phillips MA, Daneshgar N, Koh HJ, Koh A, Davis J, Devine N, Saleem M, Scudese E, Arnold KR, Vanessa Chavarin V, Daniel Robinson R, Chakraborty M, Gaddy JA, Sweetwyne MT, Wilson G, Zaganjor E, Kezos J, Dondi C, Reddy AK, Glancy B, Kirabo A, Quintana AM, Dai DF, Ocorr K, Murray SA, Damo SM, Exil V, Riggs B, Mobley BC, Gomez JA, McReynolds MR, Hinton A Jr. Vue Z, et al. Among authors: prasad p. Aging Cell. 2023 Dec;22(12):e14009. doi: 10.1111/acel.14009. Epub 2023 Nov 13. Aging Cell. 2023. PMID: 37960952 Free PMC article.
Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts.
Vue Z, Ajayi PT, Neikirk K, Murphy AC, Prasad P, Jenkins BC, Vang L, Garza-Lopez E, Mungai M, Marshall AG, Beasley HK, Killion M, Parker R, Anukodem J, Lavine K, Ajijola O, Mobley BC, Dai DF, Exil V, Kirabo A, Su YR, Tomasek K, Zhang X, Wanjalla C, Hubert DL, Phillips MA, Shao JQ, McReynolds MR, Glancy B, Hinton A Jr. Vue Z, et al. Among authors: prasad p. bioRxiv [Preprint]. 2023 Dec 14:2023.11.28.569095. doi: 10.1101/2023.11.28.569095. bioRxiv. 2023. PMID: 38076993 Free PMC article. Preprint.
The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney.
Vue Z, Prasad P, Le H, Neikirk K, Harris C, Garza-Lopez E, Wang E, Murphy A, Jenkins B, Vang L, Scudese E, Shao B, Kadam A, Shao J, Marshall AG, Crabtree A, Kirk B, Koh A, Wilson G, Oliver A, Rodman T, Kabugi K, Koh HJ, Smith Q, Zaganjor E, Wanjalla CN, Dash C, Evans C, Phillips MA, Hubert D, Ajijola O, Whiteside A, Do Koo Y, Kinder A, Demirci M, Albritton CF, Wandira N, Jamison S, Ahmed T, Saleem M, Tomar D, Williams CR, Sweetwyne MT, Murray SA, Cooper A, Kirabo A, Jadiya P, Quintana A, Katti P, Fu Dai D, McReynolds MR, Hinton A Jr. Vue Z, et al. Among authors: prasad p. bioRxiv [Preprint]. 2024 Jun 12:2024.06.09.598108. doi: 10.1101/2024.06.09.598108. bioRxiv. 2024. PMID: 38915644 Free PMC article. Preprint.
MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes.
Vue Z, Murphy A, Le H, Neikirk K, Garza-Lopez E, Marshall AG, Mungai M, Jenkins B, Vang L, Beasley HK, Ezedimma M, Manus S, Whiteside A, Forni MF, Harris C, Crabtree A, Albritton CF, Jamison S, Demirci M, Prasad P, Oliver A, Actkins KV, Shao J, Zaganjor E, Scudese E, Rodriguez B, Koh A, Rabago I, Moore JE, Nguyen D, Aftab M, Kirk B, Li Y, Wandira N, Ahmad T, Saleem M, Kadam A, Katti P, Koh HJ, Evans C, Koo YD, Wang E, Smith Q, Tomar D, Williams CR, Sweetwyne MT, Quintana AM, Phillips MA, Hubert D, Kirabo A, Dash C, Jadiya P, Kinder A, Ajijola OA, Miller-Fleming TW, McReynolds MR, Hinton A Jr. Vue Z, et al. Among authors: prasad p. bioRxiv [Preprint]. 2024 Jul 3:2024.06.20.599846. doi: 10.1101/2024.06.20.599846. bioRxiv. 2024. PMID: 38979162 Free PMC article. Preprint.
Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E. Myers JW, et al. Among authors: prasad p. bioRxiv [Preprint]. 2024 Nov 1:2024.10.28.620705. doi: 10.1101/2024.10.28.620705. bioRxiv. 2024. PMID: 39553975 Free PMC article. Preprint.
Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome.
Li S, Liu H, Hu H, Ha E, Prasad P, Jenkins BC, Das US, Mukherjee S, Shishikura K, Hu R, Rader DJ, Pei L, Baur JA, Matthews ML, FitzGerald GA, McReynolds MR, Susztak K. Li S, et al. Among authors: prasad p. Cell Metab. 2025 Jan 7;37(1):154-168.e7. doi: 10.1016/j.cmet.2024.10.007. Epub 2024 Nov 18. Cell Metab. 2025. PMID: 39561766
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Minhas PS, Jones JR, Latif-Hernandez A, Sugiura Y, Durairaj AS, Wang Q, Mhatre SD, Uenaka T, Crapser J, Conley T, Ennerfelt H, Jung YJ, Liu L, Prasad P, Jenkins BC, Ay YA, Matrongolo M, Goodman R, Newmeyer T, Heard K, Kang A, Wilson EN, Yang T, Ullian EM, Serrano GE, Beach TG, Wernig M, Rabinowitz JD, Suematsu M, Longo FM, McReynolds MR, Gage FH, Andreasson KI. Minhas PS, et al. Among authors: prasad p. Science. 2024 Aug 23;385(6711):eabm6131. doi: 10.1126/science.abm6131. Epub 2024 Aug 23. Science. 2024. PMID: 39172838
HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression.
Obare LM, Bailin SS, Zhang X, Nthenge K, Priest S, Liu Q, Stolze LK, Sheng Q, Gangula R, Behrens M, Jenkins B, Prasad P, Neikirk K, Prakash P, Hogan M, Zhang L, Beasley HK, Shao J, Miller-Fleming TW, Actkins KV, Phillips MA, Hubert D, Malone J, Labeeb C, Gelbard A, Chaillon A, Mashayekhi M, Gabriel CL, Temu T, Olson L, Jones A, Beeri K, Baker P, Kawai K, Ghosh SKB, Guo L, Virmani R, Finn A, Shah P, Yang TS, Bick AG, Kirabo A, Su YR, Phillips EJ, Mallal S, Dash C, Koethe JR, Gianella S, McReynolds MR, Absi T, Hinton A, Wanjalla CN. Obare LM, et al. Among authors: prasad p. Res Sq [Preprint]. 2024 Oct 18:rs.3.rs-5125826. doi: 10.21203/rs.3.rs-5125826/v1. Res Sq. 2024. PMID: 39483879 Free PMC article. Preprint.
2,061 results