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A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: dumlao d. bioRxiv [Preprint]. 2024 May 13:2023.11.02.565382. doi: 10.1101/2023.11.02.565382. bioRxiv. 2024. Update in: Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. PMID: 37961209 Free PMC article. Updated. Preprint.
Expansion of a bacterial operon during cancer treatment ameliorates drug toxicity.
Trepka KR, Kidder WA, Kyaw TS, Halsey T, Olson CA, Ortega EF, Noecker C, Upadhyay V, Stanfield D, Steiding P, Guthrie BGH, Spanogiannopoulos P, Dumlao D, Turnbaugh JA, Stachler MD, Van Blarigan EL, Venook AP, Atreya CE, Turnbaugh PJ. Trepka KR, et al. Among authors: dumlao d. bioRxiv [Preprint]. 2024 Oct 15:2024.06.04.597471. doi: 10.1101/2024.06.04.597471. bioRxiv. 2024. PMID: 38895199 Free PMC article. Preprint.
Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors.
Kyaw TS, Zhang C, Sandy M, Trepka K, Zhang S, Ramirez Hernandez LA, Ramirez L, Goh JJN, Yu K, Dimassa V, Bess EN, Brockert JG, Dumlao DS, Bisanz JE, Turnbaugh PJ. Kyaw TS, et al. Among authors: dumlao ds. iScience. 2024 May 27;27(6):110122. doi: 10.1016/j.isci.2024.110122. eCollection 2024 Jun 21. iScience. 2024. PMID: 38947502 Free PMC article.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: dumlao d. Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. Online ahead of print. Cell Rep. 2024. PMID: 39500329 Free article.
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
Hall J, Brault A, Vincent F, Weng S, Wang H, Dumlao D, Aulabaugh A, Aivazian D, Castro D, Chen M, Culp J, Dower K, Gardner J, Hawrylik S, Golenbock D, Hepworth D, Horn M, Jones L, Jones P, Latz E, Li J, Lin LL, Lin W, Lin D, Lovering F, Niljanskul N, Nistler R, Pierce B, Plotnikova O, Schmitt D, Shanker S, Smith J, Snyder W, Subashi T, Trujillo J, Tyminski E, Wang G, Wong J, Lefker B, Dakin L, Leach K. Hall J, et al. Among authors: dumlao d. PLoS One. 2017 Sep 21;12(9):e0184843. doi: 10.1371/journal.pone.0184843. eCollection 2017. PLoS One. 2017. PMID: 28934246 Free PMC article.
28 results