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A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: trepka k. Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. Online ahead of print. Cell Rep. 2024. PMID: 39500329 Free article.
Metagenomic analysis during capecitabine therapy reveals microbial chemoprotective mechanisms and predicts drug toxicity in colorectal cancer patients.
Hillege LE, Trepka KR, Ziemons J, Aarnoutse R, Guthrie BGH, de Vos-Geelen J, Valkenburg-van Iersel L, van Hellemond IEG, Baars A, Vestjens JHMJ, Penders J, Deutschbauer A, Atreya CE, Kidder WA, Turnbaugh PJ, Smidt ML. Hillege LE, et al. Among authors: trepka kr. medRxiv [Preprint]. 2024 Oct 15:2024.10.11.24315249. doi: 10.1101/2024.10.11.24315249. medRxiv. 2024. PMID: 39484258 Free PMC article. Preprint.
Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors.
Kyaw TS, Zhang C, Sandy M, Trepka K, Zhang S, Ramirez Hernandez LA, Ramirez L, Goh JJN, Yu K, Dimassa V, Bess EN, Brockert JG, Dumlao DS, Bisanz JE, Turnbaugh PJ. Kyaw TS, et al. Among authors: trepka k. iScience. 2024 May 27;27(6):110122. doi: 10.1016/j.isci.2024.110122. eCollection 2024 Jun 21. iScience. 2024. PMID: 38947502 Free PMC article.
Expansion of a bacterial operon during cancer treatment ameliorates drug toxicity.
Trepka KR, Kidder WA, Kyaw TS, Halsey T, Olson CA, Ortega EF, Noecker C, Upadhyay V, Stanfield D, Steiding P, Guthrie BGH, Spanogiannopoulos P, Dumlao D, Turnbaugh JA, Stachler MD, Van Blarigan EL, Venook AP, Atreya CE, Turnbaugh PJ. Trepka KR, et al. bioRxiv [Preprint]. 2024 Oct 15:2024.06.04.597471. doi: 10.1101/2024.06.04.597471. bioRxiv. 2024. PMID: 38895199 Free PMC article. Preprint.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: trepka k. bioRxiv [Preprint]. 2024 May 13:2023.11.02.565382. doi: 10.1101/2023.11.02.565382. bioRxiv. 2024. Update in: Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. PMID: 37961209 Free PMC article. Updated. Preprint.
14 results