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Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD).
Zhang T, Ambrodji A, Huang H, Bouchonville KJ, Etheridge AS, Schmidt RE, Bembenek BM, Temesgen ZB, Wang Z, Innocenti F, Stroka D, Diasio RB, Largiadèr CR, Offer SM. Zhang T, et al. Among authors: huang h. bioRxiv [Preprint]. 2024 Mar 16:2023.11.01.565230. doi: 10.1101/2023.11.01.565230. bioRxiv. 2024. Update in: Elife. 2024 Apr 30;13:RP94075. doi: 10.7554/eLife.94075. PMID: 37961517 Free PMC article. Updated. Preprint.
NAT10-mediated mRNA N4-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia.
Zhang S, Huang F, Wang Y, Long Y, Li Y, Kang Y, Gao W, Zhang X, Wen Y, Wang Y, Pan L, Xia Y, Yang Z, Yang Y, Mo H, Li B, Hu J, Song Y, Zhang S, Dong S, Du X, Li Y, Liu Y, Liao W, Gao Y, Zhang Y, Chen H, Liang Y, Chen J, Weng H, Huang H. Zhang S, et al. Among authors: huang h. Nat Cell Biol. 2024 Nov 6. doi: 10.1038/s41556-024-01548-y. Online ahead of print. Nat Cell Biol. 2024. PMID: 39506072
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