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Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity.
Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Kugeratski FG, et al. Among authors: kalluri r. bioRxiv [Preprint]. 2023 Nov 4:2023.11.02.565371. doi: 10.1101/2023.11.02.565371. bioRxiv. 2023. PMID: 37961535 Free PMC article. Preprint.
Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer.
Mahadevan KK, Dyevoich AM, Chen Y, Li B, Sugimoto H, Sockwell AM, McAndrews KM, Wang H, Shalapour S, Watowich SS, Kalluri R. Mahadevan KK, et al. Among authors: kalluri r. bioRxiv [Preprint]. 2023 Mar 6:2023.03.05.531191. doi: 10.1101/2023.03.05.531191. bioRxiv. 2023. Update in: Science. 2024 Jun 28;384(6703):eadh4567. doi: 10.1126/science.adh4567 PMID: 36945457 Free PMC article. Updated. Preprint.
Single extracellular vesicle imaging and computational analysis identifies inherent architectural heterogeneity.
Kapoor KS, Kong S, Sugimoto H, Guo W, Boominathan V, Chen YL, Biswal SL, Terlier T, McAndrews KM, Kalluri R. Kapoor KS, et al. Among authors: kalluri r. bioRxiv [Preprint]. 2023 Dec 12:2023.12.11.571132. doi: 10.1101/2023.12.11.571132. bioRxiv. 2023. Update in: ACS Nano. 2024 May 7;18(18):11717-11731. doi: 10.1021/acsnano.3c12556 PMID: 38168235 Free PMC article. Updated. Preprint.
Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity.
Luo X, McAndrews KM, Arian KA, Morse SJ, Boeker V, Kumbhar SV, Hu Y, Mahadevan KK, Church KA, Chitta S, Ryujin NT, Hensel J, Dai J, Dowlatshahi DP, Sugimoto H, Kirtley ML, LeBleu VS, Shalapour S, Simmons JH, Kalluri R. Luo X, et al. Among authors: kalluri r. J Control Release. 2024 Oct;374:550-562. doi: 10.1016/j.jconrel.2024.08.017. Epub 2024 Aug 30. J Control Release. 2024. PMID: 39146981
Genetics and biology of pancreatic ductal adenocarcinoma.
Ying H, Kimmelman AC, Bardeesy N, Kalluri R, Maitra A, DePinho RA. Ying H, et al. Among authors: kalluri r. Genes Dev. 2024 Nov 7. doi: 10.1101/gad.351863.124. Online ahead of print. Genes Dev. 2024. PMID: 39510840 Review.
Vascular heterogeneity of tight junction Claudins guides organotropic metastasis.
Zhou X, LeBleu VS, Fletcher-Sananikone E, Kim J, Dai J, Li B, Wu CC, Sugimoto H, Miyake T, Becker LM, Volpert OV, Lawson E, Espinosa Da Silva C, Patel SI, Kizu A, Ehsanipour EA, Sha D, Karam JA, McAndrews KM, Kalluri R. Zhou X, et al. Among authors: kalluri r. Nat Cancer. 2024 Sep;5(9):1371-1389. doi: 10.1038/s43018-024-00813-1. Epub 2024 Sep 17. Nat Cancer. 2024. PMID: 39289595
392 results