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Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy.
Kober C, Roewe J, Schmees N, Roese L, Roehn U, Bader B, Stoeckigt D, Prinz F, Gorjánácz M, Roider HG, Olesch C, Leder G, Irlbacher H, Lesche R, Lefranc J, Oezcan-Wahlbrink M, Batra AS, Elmadany N, Carretero R, Sahm K, Oezen I, Cichon F, Baumann D, Sadik A, Opitz CA, Weinmann H, Hartung IV, Kreft B, Offringa R, Platten M, Gutcher I. Kober C, et al. Among authors: offringa r. J Immunother Cancer. 2023 Nov;11(11):e007495. doi: 10.1136/jitc-2023-007495. J Immunother Cancer. 2023. PMID: 37963637 Free PMC article.
optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material.
Salek M, Förster JD, Becker JP, Meyer M, Charoentong P, Lyu Y, Lindner K, Lotsch C, Volkmar M, Momburg F, Poschke I, Fröhling S, Schmitz M, Offringa R, Platten M, Jäger D, Zörnig I, Riemer AB. Salek M, et al. Among authors: offringa r. Mol Cell Proteomics. 2024 Sep;23(9):100825. doi: 10.1016/j.mcpro.2024.100825. Epub 2024 Aug 5. Mol Cell Proteomics. 2024. PMID: 39111711 Free PMC article.
Secretogranin II influences the assembly and function of MHC class I in melanoma.
Steinfass T, Poelchen J, Sun Q, Mastrogiulio G, Novak D, Vierthaler M, Pardo S, Federico A, Hüser L, Hielscher T, Carretero R, Offringa R, Altevogt P, Umansky V, Utikal J. Steinfass T, et al. Among authors: offringa r. Exp Hematol Oncol. 2023 Mar 11;12(1):29. doi: 10.1186/s40164-023-00387-1. Exp Hematol Oncol. 2023. PMID: 36906639 Free PMC article.
Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
Tan CL, Lindner K, Boschert T, Meng Z, Rodriguez Ehrenfried A, De Roia A, Haltenhof G, Faenza A, Imperatore F, Bunse L, Lindner JM, Harbottle RP, Ratliff M, Offringa R, Poschke I, Platten M, Green EW. Tan CL, et al. Among authors: offringa r. Nat Biotechnol. 2025 Jan;43(1):134-142. doi: 10.1038/s41587-024-02161-y. Epub 2024 Mar 7. Nat Biotechnol. 2025. PMID: 38454173 Free PMC article.
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer.
Mowat J, Carretero R, Leder G, Aiguabella Font N, Neuhaus R, Berndt S, Günther J, Friberg A, Schäfer M, Briem H, Raschke M, Miyatake Ondozabal H, Buchmann B, Boemer U, Kreft B, Hartung IV, Offringa R. Mowat J, et al. Among authors: offringa r. J Med Chem. 2024 Oct 10;67(19):17429-17453. doi: 10.1021/acs.jmedchem.4c01325. Epub 2024 Sep 27. J Med Chem. 2024. PMID: 39331123 Free PMC article.
267 results