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Time-resolved live-cell spectroscopy reveals EphA2 multimeric assembly.
Shi X, Lingerak R, Herting CJ, Ge Y, Kim S, Toth P, Wang W, Brown BP, Meiler J, Sossey-Alaoui K, Buck M, Himanen J, Hambardzumyan D, Nikolov DB, Smith AW, Wang B. Shi X, et al. Among authors: brown bp. Science. 2023 Dec;382(6674):1042-1050. doi: 10.1126/science.adg5314. Epub 2023 Nov 16. Science. 2023. PMID: 37972196 Free PMC article.
Lipocalin Blc is a potential heme-binding protein.
Bozhanova NG, Calcutt MW, Beavers WN, Brown BP, Skaar EP, Meiler J. Bozhanova NG, et al. Among authors: brown bp. FEBS Lett. 2021 Jan;595(2):206-219. doi: 10.1002/1873-3468.14001. Epub 2020 Dec 3. FEBS Lett. 2021. PMID: 33210733 Free PMC article.
Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting.
Du Z, Brown BP, Kim S, Ferguson D, Pavlick DC, Jayakumaran G, Benayed R, Gallant JN, Zhang YK, Yan Y, Red-Brewer M, Ali SM, Schrock AB, Zehir A, Ladanyi M, Smith AW, Meiler J, Lovly CM. Du Z, et al. Among authors: brown bp. Nat Commun. 2021 Mar 2;12(1):1382. doi: 10.1038/s41467-021-21613-6. Nat Commun. 2021. PMID: 33654076 Free PMC article.
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.
Hanker AB, Brown BP, Meiler J, Marín A, Jayanthan HS, Ye D, Lin CC, Akamatsu H, Lee KM, Chatterjee S, Sudhan DR, Servetto A, Brewer MR, Koch JP, Sheehan JH, He J, Lalani AS, Arteaga CL. Hanker AB, et al. Among authors: brown bp. Cancer Cell. 2021 Aug 9;39(8):1099-1114.e8. doi: 10.1016/j.ccell.2021.06.001. Epub 2021 Jun 24. Cancer Cell. 2021. PMID: 34171264 Free PMC article.
171 results