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21 results

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Page 1
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
Ozyerli-Goknar E, Kala EY, Aksu AC, Bulut I, Cingöz A, Nizamuddin S, Biniossek M, Seker-Polat F, Morova T, Aztekin C, Kung SHY, Syed H, Tuncbag N, Gönen M, Philpott M, Cribbs AP, Acilan C, Lack NA, Onder TT, Timmers HTM, Bagci-Onder T. Ozyerli-Goknar E, et al. Among authors: kung shy. Cell Commun Signal. 2023 Nov 16;21(1):328. doi: 10.1186/s12964-023-01335-6. Cell Commun Signal. 2023. PMID: 37974198 Free PMC article.
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities.
Yedier-Bayram O, Gokbayrak B, Kayabolen A, Aksu AC, Cavga AD, Cingöz A, Kala EY, Karabiyik G, Günsay R, Esin B, Morova T, Uyulur F, Syed H, Philpott M, Cribbs AP, Kung SHY, Lack NA, Onder TT, Bagci-Onder T. Yedier-Bayram O, et al. Among authors: kung shy. Cell Death Dis. 2022 Aug 16;13(8):710. doi: 10.1038/s41419-022-05146-4. Cell Death Dis. 2022. PMID: 35973998 Free PMC article.
Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression.
Zhang F, Biswas M, Massah S, Lee J, Lingadahalli S, Wong S, Wells C, Foo J, Khan N, Morin H, Saxena N, Kung SHY, Sun B, Parra Nuñez AK, Sanchez C, Chan N, Ung L, Altıntaş UB, Bui JM, Wang Y, Fazli L, Oo HZ, Rennie PS, Lack NA, Cherkasov A, Gleave ME, Gsponer J, Lallous N. Zhang F, et al. Among authors: kung shy. Nucleic Acids Res. 2023 Jan 11;51(1):99-116. doi: 10.1093/nar/gkac1158. Nucleic Acids Res. 2023. PMID: 36535377 Free PMC article.
Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling.
Nath D, Li X, Mondragon C, Post D, Chen M, White JR, Hryniewicz-Jankowska A, Caza T, Kuznetsov VA, Hehnly H, Jamaspishvili T, Berman DM, Zhang F, Kung SHY, Fazli L, Gleave ME, Bratslavsky G, Pandolfi PP, Kotula L. Nath D, et al. Among authors: kung shy. Cell Commun Signal. 2019 Sep 18;17(1):120. doi: 10.1186/s12964-019-0410-y. Cell Commun Signal. 2019. PMID: 31530281 Free PMC article.
Macrophages, Inflammation, and Lung Cancer.
Conway EM, Pikor LA, Kung SH, Hamilton MJ, Lam S, Lam WL, Bennewith KL. Conway EM, et al. Am J Respir Crit Care Med. 2016 Jan 15;193(2):116-30. doi: 10.1164/rccm.201508-1545CI. Am J Respir Crit Care Med. 2016. PMID: 26583808
A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma.
Ramos L, Truong S, Zhai B, Joshi J, Ghaidi F, Lizardo MM, Shyp T, Kung SHY, Rezakhanlou AM, Oo HZ, Adomat H, Le Bihan S, Collins C, Bacha J, Brown D, Langlands J, Shen W, Lallous N, Sorensen PH, Daugaard M. Ramos L, et al. Among authors: kung shy. Clin Cancer Res. 2023 Sep 1;29(17):3541-3553. doi: 10.1158/1078-0432.CCR-22-3897. Clin Cancer Res. 2023. PMID: 37279093 Free PMC article.
A MYCN-independent mechanism mediating secretome reprogramming and metastasis in MYCN-amplified neuroblastoma.
Zhang HF, Delaidelli A, Javed S, Turgu B, Morrison T, Hughes CS, Yang X, Pachva M, Lizardo MM, Singh G, Hoffmann J, Huang YZ, Patel K, Shraim R, Kung SHY, Morin GB, Aparicio S, Martinez D, Maris JM, Bosse KR, Williams KC, Sorensen PH. Zhang HF, et al. Among authors: kung shy. Sci Adv. 2023 Aug 25;9(34):eadg6693. doi: 10.1126/sciadv.adg6693. Epub 2023 Aug 23. Sci Adv. 2023. PMID: 37611092 Free PMC article.
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2.
Kaarijärvi R, Kaljunen H, Nappi L, Fazli L, Kung SHY, Hartikainen JM, Paakinaho V, Capra J, Rilla K, Malinen M, Mäkinen PI, Ylä-Herttuala S, Zoubeidi A, Wang Y, Gleave ME, Hiltunen M, Ketola K. Kaarijärvi R, et al. Among authors: kung shy. Commun Biol. 2024 Jan 18;7(1):108. doi: 10.1038/s42003-023-05741-x. Commun Biol. 2024. PMID: 38238517 Free PMC article.
21 results