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Why Single-Cell Sequencing Has Promise in MDS.
Zhang X, Grimes HL. Zhang X, et al. Among authors: grimes hl. Front Oncol. 2021 Dec 2;11:769753. doi: 10.3389/fonc.2021.769753. eCollection 2021. Front Oncol. 2021. PMID: 34926276 Free PMC article. Review.
Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis.
Drucker M, Lee D, Zhang X, Kain B, Bowman M, Nicolet D, Wang Z, Stone RM, Mrózek K, Carroll AJ, Starczynowski DT, Levine RL, Byrd JC, Eisfeld AK, Salomonis N, Grimes HL, Bowman RL, Miles LA. Drucker M, et al. Among authors: grimes hl. bioRxiv [Preprint]. 2024 Nov 12:2024.11.11.623033. doi: 10.1101/2024.11.11.623033. bioRxiv. 2024. PMID: 39605444 Free PMC article. Preprint.
Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia.
Stiff A, Fornerod M, Kain BN, Nicolet D, Kelly BJ, Miller KE, Mrózek K, Boateng I, Bollas A, Garfinkle EAR, Momoh O, Fasola FA, Olawumi HO, Mencia-Trinchant N, Kloppers JF, van Marle AC, Hu E, Wijeratne S, Wheeler G, Walker CJ, Buss J, Heyrosa A, Desai H, Laganson A, Hamp E, Abu-Shihab Y, Abaza H, Kronen P, Sen S, Johnstone ME, Quinn K, Wronowski B, Hertlein E, Miles LA, Mims AS, Oakes CC, Blachly JS, Larkin KT, Mundy-Bosse B, Carroll AJ, Powell BL, Kolitz JE, Stone RM, Duarte C, Abbott D, Amaya ML, Jordan CT, Uy GL, Stock W, Archer KJ, Paskett ED, Guzman ML, Levine RL, Menghrajani K, Chakravarty D, Berger MF, Bottomly D, McWeeney SK, Tyner JW, Byrd JC, Salomonis N, Grimes HL, Mardis ER, Eisfeld AK. Stiff A, et al. Among authors: grimes hl. Nat Genet. 2024 Nov;56(11):2434-2446. doi: 10.1038/s41588-024-01929-x. Epub 2024 Oct 4. Nat Genet. 2024. PMID: 39367245 Free PMC article.
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.
Zhang X, Song B, Carlino MJ, Li G, Ferchen K, Chen M, Thompson EN, Kain BN, Schnell D, Thakkar K, Kouril M, Jin K, Hay SB, Sen S, Bernardicius D, Ma S, Bennett SN, Croteau J, Salvatori O, Lye MH, Gillen AE, Jordan CT, Singh H, Krause DS, Salomonis N, Grimes HL. Zhang X, et al. Among authors: grimes hl. Nat Immunol. 2024 Apr;25(4):703-715. doi: 10.1038/s41590-024-01782-4. Epub 2024 Mar 21. Nat Immunol. 2024. PMID: 38514887 Free PMC article.
Resilient anatomy and local plasticity of naive and stress haematopoiesis.
Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D. Wu Q, et al. Among authors: grimes hl. Nature. 2024 Mar;627(8005):839-846. doi: 10.1038/s41586-024-07186-6. Epub 2024 Mar 20. Nature. 2024. PMID: 38509363 Free PMC article.
Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation.
Venkatasubramanian M, Schwartz L, Ramachandra N, Bennett J, Subramanian KR, Chen X, Gordon-Mitchell S, Fromowitz A, Pradhan K, Shechter D, Sahu S, Heiser D, Scherle P, Chetal K, Kulkarni A, Myers KC, Weirauch MT, Grimes HL, Starczynowski DT, Verma A, Salomonis N. Venkatasubramanian M, et al. Among authors: grimes hl. bioRxiv [Preprint]. 2024 Feb 8:2024.02.04.578798. doi: 10.1101/2024.02.04.578798. bioRxiv. 2024. PMID: 38370617 Free PMC article. Preprint.
139 results