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Page 1
HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agents.
Waitman KB, de Almeida LC, Primi MC, Carlos JAEG, Ruiz C, Kronenberger T, Laufer S, Goettert MI, Poso A, Vassiliades SV, de Souza VAM, Toledo MFZJ, Hassimotto NMA, Cameron MD, Bannister TD, Costa-Lotufo LV, Machado-Neto JA, Tavares MT, Parise-Filho R. Waitman KB, et al. Eur J Med Chem. 2024 Jan 5;263:115935. doi: 10.1016/j.ejmech.2023.115935. Epub 2023 Nov 10. Eur J Med Chem. 2024. PMID: 37989057
1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors.
Tavares MT, Krüger A, Yan SLR, Waitman KB, Gomes VM, de Oliveira DS, Paz F, Hilscher S, Schutkowski M, Sippl W, Ruiz C, Toledo MFZJ, Hassimotto NMA, Machado-Neto JA, Poso A, Cameron MD, Bannister TD, Palmisano G, Wrenger C, Kronenberger T, Parise-Filho R. Tavares MT, et al. Among authors: waitman kb. Sci Rep. 2023 Nov 29;13(1):21006. doi: 10.1038/s41598-023-47959-z. Sci Rep. 2023. PMID: 38030668 Free PMC article.
Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors.
da Silva GM, de Souza DHB, Waitman KB, Ebram MC, Fessel MR, Zainescu IC, Portaro FC, Heras M, de Andrade SA. da Silva GM, et al. Among authors: waitman kb. J Venom Anim Toxins Incl Trop Dis. 2021 Jan 15;27:e20200066. doi: 10.1590/1678-9199-JVATITD-2020-0066. eCollection 2021. J Venom Anim Toxins Incl Trop Dis. 2021. PMID: 33488681 Free PMC article.
Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment.
Waitman KB, Martin HJ, Carlos JAEG, Braga RC, Souza VAM, Melo-Filho CC, Hilscher S, Toledo MFZJ, Tavares MT, Costa-Lotufo LV, Machado-Neto JA, Schutkowski M, Sippl W, Kronenberger T, Alves VM, Parise-Filho R, Muratov EN. Waitman KB, et al. bioRxiv [Preprint]. 2024 Dec 5:2024.11.30.626092. doi: 10.1101/2024.11.30.626092. bioRxiv. 2024. PMID: 39677737 Free PMC article. Preprint.