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Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids.
Dhaliwal NK, Weng OY, Dong X, Bhattacharya A, Ahmed M, Nishimura H, Choi WWY, Aggarwal A, Luikart BW, Shu Q, Li X, Wilson MD, Moffat J, Wang LY, Muffat J, Li Y. Dhaliwal NK, et al. Among authors: li y, li x. Cell Rep. 2024 May 28;43(5):114173. doi: 10.1016/j.celrep.2024.114173. Epub 2024 May 2. Cell Rep. 2024. PMID: 38700984 Free article.
RYBP modulates stability and function of Ring1B through targeting UBE3A.
Li M, Zhang S, Zhao W, Hou C, Ma X, Li X, Huang B, Chen H, Chen D. Li M, et al. Among authors: li x. FASEB J. 2019 Jan;33(1):683-695. doi: 10.1096/fj.201800397R. Epub 2018 Jul 24. FASEB J. 2019. PMID: 30040487
Thus, our current findings lay a foundation for understanding how RYBP functions in nc-PRC1 complexes, which is involved in development, stem cell maintenance, and carcinogenesis.-Li, M., Zhang, S., Zhao, W., Hou, C., Ma, X., Li, X., Huang, B., Chen, H …
Thus, our current findings lay a foundation for understanding how RYBP functions in nc-PRC1 complexes, which is involved in development, ste …
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