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RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS.
Shimizu M, Shiraishi N, Tada S, Sasaki T, Beck G, Nagano S, Kinoshita M, Sumi H, Sugimoto T, Ishida Y, Koda T, Ishikura T, Sugiyama Y, Kihara K, Kanakura M, Nakajima T, Takeda S, Takahashi MP, Yamashita T, Okuno T, Mochizuki H. Shimizu M, et al. Among authors: sugiyama y. Sci Adv. 2023 Nov 24;9(47):eadg3193. doi: 10.1126/sciadv.adg3193. Epub 2023 Nov 22. Sci Adv. 2023. PMID: 37992159 Free PMC article.
Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation.
Shimizu M, Okuno T, Kinoshita M, Sumi H, Fujimura H, Yamashita K, Sugimoto T, Sakakibara S, Sakakibara K, Koda T, Tada S, Ishikura T, Murata H, Beppu S, Shiraishi N, Sugiyama Y, Nakatsuji Y, Kumanogoh A, Mochizuki H. Shimizu M, et al. Among authors: sugiyama y. Sci Rep. 2020 Aug 6;10(1):13274. doi: 10.1038/s41598-020-70203-x. Sci Rep. 2020. PMID: 32764561 Free PMC article.
Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats.
Ishikura T, Kinoshita M, Shimizu M, Yasumizu Y, Motooka D, Okuzaki D, Yamashita K, Murata H, Beppu S, Koda T, Tada S, Shiraishi N, Sugiyama Y, Miyamoto K, Kusunoki S, Sugimoto T, Kumanogoh A, Okuno T, Mochizuki H. Ishikura T, et al. Among authors: sugiyama y. J Neuroinflammation. 2021 Aug 21;18(1):181. doi: 10.1186/s12974-021-02232-w. J Neuroinflammation. 2021. PMID: 34419102 Free PMC article.
High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD).
Beppu S, Kinoshita M, Wilamowski J, Suenaga T, Yasumizu Y, Ogawa K, Ishikura T, Tada S, Koda T, Murata H, Shiraishi N, Sugiyama Y, Kihara K, Sugimoto T, Arase H, Standley DM, Okuno T, Mochizuki H. Beppu S, et al. Among authors: sugiyama y. Sci Rep. 2022 Jan 7;12(1):106. doi: 10.1038/s41598-021-04074-1. Sci Rep. 2022. PMID: 34997058 Free PMC article.
Cell-Free DNA Derived From Neutrophils Triggers Type 1 Interferon Signature in Neuromyelitis Optica Spectrum Disorder.
Murata H, Kinoshita M, Yasumizu Y, Motooka D, Beppu S, Shiraishi N, Sugiyama Y, Kihara K, Tada S, Koda T, Konaka H, Takamatsu H, Kumanogoh A, Okuno T, Mochizuki H. Murata H, et al. Among authors: sugiyama y. Neurol Neuroimmunol Neuroinflamm. 2022 Feb 24;9(3):e1149. doi: 10.1212/NXI.0000000000001149. Print 2022 May. Neurol Neuroimmunol Neuroinflamm. 2022. PMID: 35210295 Free PMC article.
Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production.
Sugiyama Y, Takata K, Kinoshita M, Motooka D, Shiraishi N, Kihara K, Murata H, Beppu S, Koda T, Yamashita K, Namba A, Fujimoto K, Kumanogoh A, Okuno T, Mochizuki H. Sugiyama Y, et al. Biochem Biophys Res Commun. 2023 May 14;656:97-103. doi: 10.1016/j.bbrc.2023.03.041. Epub 2023 Mar 16. Biochem Biophys Res Commun. 2023. PMID: 36958260 No abstract available.
Switching disease-modifying therapies from sphingosine-1-phosphate receptor modulators to natalizumab or dimethyl fumarate restores immune responses after SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis.
Kanakura M, Kihara K, Kinoshita M, Sugimoto T, Murata H, Beppu S, Shiraishi N, Sugiyama Y, Koda T, Takahashi MP, Chinen I, Okuno T, Mochizuki H. Kanakura M, et al. Among authors: sugiyama y. Clin Neurol Neurosurg. 2024 Aug;243:108378. doi: 10.1016/j.clineuro.2024.108378. Epub 2024 Jun 15. Clin Neurol Neurosurg. 2024. PMID: 38901377 Free article.
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory.
Kidani Y, Nogami W, Yasumizu Y, Kawashima A, Tanaka A, Sonoda Y, Tona Y, Nashiki K, Matsumoto R, Hagiwara M, Osaki M, Dohi K, Kanazawa T, Ueyama A, Yoshikawa M, Yoshida T, Matsumoto M, Hojo K, Shinonome S, Yoshida H, Hirata M, Haruna M, Nakamura Y, Motooka D, Okuzaki D, Sugiyama Y, Kinoshita M, Okuno T, Kato T, Hatano K, Uemura M, Imamura R, Yokoi K, Tanemura A, Shintani Y, Kimura T, Nonomura N, Wada H, Mori M, Doki Y, Ohkura N, Sakaguchi S. Kidani Y, et al. Among authors: sugiyama y. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2114282119. doi: 10.1073/pnas.2114282119. Proc Natl Acad Sci U S A. 2022. PMID: 35140181 Free PMC article.
Functional recoveries of patients with branch atheromatous disease after rehabilitation: Comparison with other types of cerebral infarction and importance of stratification by clinical categories.
Okuda Y, Aoike F, Matsuzaki J, Shiraishi S, Sugiyama S, Yoshida T, Kitamura E, Nishida F, Tanaka N, Sugiyama Y, Enami T, Yanagihara T. Okuda Y, et al. Among authors: sugiyama s, sugiyama y. Restor Neurol Neurosci. 2021;39(2):139-147. doi: 10.3233/RNN-211163. Restor Neurol Neurosci. 2021. PMID: 33967074
2,696 results