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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Patel AP, Wang M, Ruan Y, Koyama S, Clarke SL, Yang X, Tcheandjieu C, Agrawal S, Fahed AC, Ellinor PT; Genes & Health Research Team; the Million Veteran Program; Tsao PS, Sun YV, Cho K, Wilson PWF, Assimes TL, van Heel DA, Butterworth AS, Aragam KG, Natarajan P, Khera AV. Patel AP, et al. Among authors: fahed ac. Nat Med. 2023 Jul;29(7):1793-1803. doi: 10.1038/s41591-023-02429-x. Epub 2023 Jul 6. Nat Med. 2023. PMID: 37414900 Free PMC article.
Clinical utility of polygenic scores for cardiometabolic disease in Arabs.
Shim I, Kuwahara H, Chen N, Hashem MO, AlAbdi L, Abouelhoda M, Won HH, Natarajan P, Ellinor PT, Khera AV, Gao X, Alkuraya FS, Fahed AC. Shim I, et al. Among authors: fahed ac. Nat Commun. 2023 Oct 18;14(1):6535. doi: 10.1038/s41467-023-41985-1. Nat Commun. 2023. PMID: 37852978 Free PMC article.
Polygenic Risk Is Associated With Long-Term Coronary Plaque Progression and High-Risk Plaque.
Nurmohamed NS, Shim I, Gaillard EL, Ibrahim S, Bom MJ, Earls JP, Min JK, Planken RN, Choi AD, Natarajan P, Stroes ESG, Knaapen P, Reeskamp LF, Fahed AC. Nurmohamed NS, et al. Among authors: fahed ac. JACC Cardiovasc Imaging. 2024 Dec;17(12):1445-1459. doi: 10.1016/j.jcmg.2024.06.015. Epub 2024 Aug 14. JACC Cardiovasc Imaging. 2024. PMID: 39152960 Free article.
Multivariate genomic analysis of 5 million people elucidates the genetic architecture of shared components of the metabolic syndrome.
Park S, Kim S, Kim B, Kim DS, Kim J, Ahn Y, Kim H, Song M, Shim I, Jung SH, Cho C, Lim S, Hong S, Jo H, Fahed AC, Natarajan P, Ellinor PT, Torkamani A, Park WY, Yu TY, Myung W, Won HH. Park S, et al. Among authors: fahed ac. Nat Genet. 2024 Nov;56(11):2380-2391. doi: 10.1038/s41588-024-01933-1. Epub 2024 Sep 30. Nat Genet. 2024. PMID: 39349817 Free PMC article.
60 results