McMahon DB - Search Results

1

Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14.

Miller ZA, Mueller A, Kim T, Jolivert JF, Ma RZ, Muthuswami S, Park A, McMahon DB, Nead KT, Carey RM, Lee RJ. Miller ZA, et al. Among authors: mcmahon db. Cell Rep. 2023 Dec 26;42(12):113437. doi: 10.1016/j.celrep.2023.113437. Epub 2023 Nov 22. Cell Rep. 2023. PMID: 37995679 Free PMC article.

2

T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma.

Carey RM, McMahon DB, Miller ZA, Kim T, Rajasekaran K, Gopallawa I, Newman JG, Basu D, Nead KT, White EA, Lee RJ. Carey RM, et al. Among authors: mcmahon db. Mol Oncol. 2022 Apr;16(7):1474-1492. doi: 10.1002/1878-0261.13131. Epub 2021 Dec 14. Mol Oncol. 2022. PMID: 34717036 Free PMC article.

3

[No title available]

[No authors listed] [No authors listed] PMID: 35552676

4

The bitter end: T2R bitter receptor agonists elevate nuclear calcium and induce apoptosis in non-ciliated airway epithelial cells.

McMahon DB, Kuek LE, Johnson ME, Johnson PO, Horn RLJ, Carey RM, Adappa ND, Palmer JN, Lee RJ. McMahon DB, et al. Cell Calcium. 2022 Jan;101:102499. doi: 10.1016/j.ceca.2021.102499. Epub 2021 Nov 8. Cell Calcium. 2022. PMID: 34839223 Free PMC article.

5

Cilia Stimulatory and Antibacterial Activities of T2R Bitter Taste Receptor Agonist Diphenhydramine: Insights into Repurposing Bitter Drugs for Nasal Infections.

Kuek LE, McMahon DB, Ma RZ, Miller ZA, Jolivert JF, Adappa ND, Palmer JN, Lee RJ. Kuek LE, et al. Among authors: mcmahon db. Pharmaceuticals (Basel). 2022 Apr 6;15(4):452. doi: 10.3390/ph15040452. Pharmaceuticals (Basel). 2022. PMID: 35455449 Free PMC article.

6

Savory Signaling: T1R Umami Receptor Modulates Endoplasmic Reticulum Calcium Store Content and Release Dynamics in Airway Epithelial Cells.

McMahon DB, Jolivert JF, Kuek LE, Adappa ND, Palmer JN, Lee RJ. McMahon DB, et al. Nutrients. 2023 Jan 18;15(3):493. doi: 10.3390/nu15030493. Nutrients. 2023. PMID: 36771200 Free PMC article.

7

Utilizing the Off-Target Effects of T1R3 Antagonist Lactisole to Enhance Nitric Oxide Production in Basal Airway Epithelial Cells.

McMahon DB, Jolivert JF, Kuek LE, Adappa ND, Palmer JN, Lee RJ. McMahon DB, et al. Nutrients. 2023 Jan 19;15(3):517. doi: 10.3390/nu15030517. Nutrients. 2023. PMID: 36771227 Free PMC article.

8

Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor.

Hariri BM, McMahon DB, Chen B, Freund JR, Mansfield CJ, Doghramji LJ, Adappa ND, Palmer JN, Kennedy DW, Reed DR, Jiang P, Lee RJ. Hariri BM, et al. Among authors: mcmahon db. J Biol Chem. 2017 May 19;292(20):8484-8497. doi: 10.1074/jbc.M116.771949. Epub 2017 Apr 3. J Biol Chem. 2017. PMID: 28373278 Free PMC article.

9

PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa.

McMahon DB, Carey RM, Kohanski MA, Adappa ND, Palmer JN, Lee RJ. McMahon DB, et al. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L845-L879. doi: 10.1152/ajplung.00411.2020. Epub 2021 Mar 3. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33655758 Free PMC article.

10

Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity.

Yan CH, Hahn S, McMahon D, Bonislawski D, Kennedy DW, Adappa ND, Palmer JN, Jiang P, Lee RJ, Cohen NA. Yan CH, et al. Am J Rhinol Allergy. 2017 Mar 1;31(2):85-92. doi: 10.2500/ajra.2017.31.4424. Am J Rhinol Allergy. 2017. PMID: 28452704 Free PMC article.

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