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Page 1
Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge Model.
Wang X, Su H, Wallach JB, Wagner JC, Braunecker B, Gardner M, Guinn KM, Klevorn T, Lin K, Liu YJ, Liu Y, Mugahid D, Rodgers M, Sixsmith J, Wakabayashi S, Zhu J, Zimmerman M, Dartois V, Flynn JL, Lin PL, Ehrt S, Fortune SM, Rubin EJ, Schnappinger D. Wang X, et al. Among authors: guinn km. bioRxiv [Preprint]. 2023 Nov 19:2023.11.19.567569. doi: 10.1101/2023.11.19.567569. bioRxiv. 2023. PMID: 38014062 Free PMC article. Preprint.
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.
Koh EI, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A, Zimmerman MD, Aslebagh R, Baker RE, Shaffer SA, Guinn KM, Fitzgerald M, Dartois V, Ehrt S, Hung DT, Ioerger TR, Rubin EJ, Rhee KY, Schnappinger D, Sassetti CM. Koh EI, et al. Among authors: guinn km. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2201632119. doi: 10.1073/pnas.2201632119. Epub 2022 Apr 5. Proc Natl Acad Sci U S A. 2022. PMID: 35380903 Free PMC article.
Implementing New Approaches to Tuberculosis Control.
Guinn KM, Rubin EJ. Guinn KM, et al. China CDC Wkly. 2021 Mar 19;3(12):256-259. doi: 10.46234/ccdcw2021.053. China CDC Wkly. 2021. PMID: 34594861 Free PMC article. No abstract available.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, Golas AJ, Guinn KM, Kennedy S, Korn R, McConnell JA, Moss CE, Murphy KC, Nietupski RM, Papavinasasundaram KG, Pinkham JT, Pino PA, Proulx MK, Ruecker N, Song N, Thompson M, Trujillo C, Wakabayashi S, Wallach JB, Watson C, Ioerger TR, Lander ES, Hubbard BK, Serrano-Wu MH, Ehrt S, Fitzgerald M, Rubin EJ, Sassetti CM, Schnappinger D, Hung DT. Johnson EO, et al. Among authors: guinn km. Nature. 2019 Jul;571(7763):72-78. doi: 10.1038/s41586-019-1315-z. Epub 2019 Jun 19. Nature. 2019. PMID: 31217586
Tuberculosis: Just the FAQs.
Guinn KM, Rubin EJ. Guinn KM, et al. mBio. 2017 Dec 19;8(6):e01910-17. doi: 10.1128/mBio.01910-17. mBio. 2017. PMID: 29259086 Free PMC article. Review.
Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.
Ioerger TR, O'Malley T, Liao R, Guinn KM, Hickey MJ, Mohaideen N, Murphy KC, Boshoff HI, Mizrahi V, Rubin EJ, Sassetti CM, Barry CE 3rd, Sherman DR, Parish T, Sacchettini JC. Ioerger TR, et al. Among authors: guinn km. PLoS One. 2013 Sep 23;8(9):e75245. doi: 10.1371/journal.pone.0075245. eCollection 2013. PLoS One. 2013. PMID: 24086479 Free PMC article.
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection.
Lin PL, Dietrich J, Tan E, Abalos RM, Burgos J, Bigbee C, Bigbee M, Milk L, Gideon HP, Rodgers M, Cochran C, Guinn KM, Sherman DR, Klein E, Janssen C, Flynn JL, Andersen P. Lin PL, et al. Among authors: guinn km. J Clin Invest. 2012 Jan;122(1):303-14. doi: 10.1172/JCI46252. Epub 2011 Dec 1. J Clin Invest. 2012. PMID: 22133873 Free PMC article.
13 results