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TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo.
Kime J, Bose D, Arainga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Marinelli E. Kime J, et al. Among authors: cicala c. bioRxiv [Preprint]. 2023 Dec 15:2023.09.05.556422. doi: 10.1101/2023.09.05.556422. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 14;15(1):1348. doi: 10.1038/s41467-024-45555-x PMID: 38014094 Free PMC article. Updated. Preprint.
The Role of Integrin α4β7 in HIV Pathogenesis and Treatment.
Arthos J, Cicala C, Nawaz F, Byrareddy SN, Villinger F, Santangelo PJ, Ansari AA, Fauci AS. Arthos J, et al. Among authors: cicala c. Curr HIV/AIDS Rep. 2018 Apr;15(2):127-135. doi: 10.1007/s11904-018-0382-3. Curr HIV/AIDS Rep. 2018. PMID: 29478152 Free PMC article. Review.
SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution.
Siqueira JD, Goes LR, Alves BM, de Carvalho PS, Cicala C, Arthos J, Viola JPB, de Melo AC, Soares MA. Siqueira JD, et al. Among authors: cicala c. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.267831. doi: 10.1101/2020.08.26.267831. bioRxiv. 2020. Update in: Virus Evol. 2021 Feb 16;7(1):veab013. doi: 10.1093/ve/veab013 PMID: 32869023 Free PMC article. Updated. Preprint.
Blocking α4β7 integrin delays viral rebound in SHIVSF162P3-infected macaques treated with anti-HIV broadly neutralizing antibodies.
Frank I, Cigoli M, Arif MS, Fahlberg MD, Maldonado S, Calenda G, Pegu A, Yang ES, Rawi R, Chuang GY, Geng H, Liu C, Zhou T, Kwong PD, Arthos J, Cicala C, Grasperge BF, Blanchard JL, Gettie A, Fennessey CM, Keele BF, Vaccari M, Hope TJ, Fauci AS, Mascola JR, Martinelli E. Frank I, et al. Among authors: cicala c. Sci Transl Med. 2021 Aug 18;13(607):eabf7201. doi: 10.1126/scitranslmed.abf7201. Sci Transl Med. 2021. PMID: 34408080 Free PMC article.
Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo.
Samer S, Thomas Y, Araínga M, Carter C, Shirreff LM, Arif MS, Avita JM, Frank I, McRaven MD, Thuruthiyil CT, Heybeli VB, Anderson MR, Owen B, Gaisin A, Bose D, Simons LM, Hultquist JF, Arthos J, Cicala C, Sereti I, Santangelo PJ, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Martinelli E. Samer S, et al. Among authors: cicala c. JCI Insight. 2022 Nov 8;7(21):e162290. doi: 10.1172/jci.insight.162290. JCI Insight. 2022. PMID: 36125890 Free PMC article.
Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage.
Park C, Hwang IY, Yan SL, Vimonpatranon S, Wei D, Van Ryk D, Girard A, Cicala C, Arthos J, Kehrl JH. Park C, et al. Among authors: cicala c. bioRxiv [Preprint]. 2023 Dec 4:2023.03.13.532446. doi: 10.1101/2023.03.13.532446. bioRxiv. 2023. Update in: Elife. 2024 Mar 20;12:RP86764. doi: 10.7554/eLife.86764 PMID: 37090605 Free PMC article. Updated. Preprint.
Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo.
Samer S, Thomas Y, Araínga M, Carter C, Shirreff LM, Arif MS, Avita JM, Frank I, McRaven MD, Thuruthiyil CT, Heybeli VB, Anderson MR, Owen B, Gaisin A, Bose D, Simons LM, Hultquist JF, Arthos J, Cicala C, Sereti I, Santangelo PJ, Lorenzo-Redondo R, Hope TJ, Villinger FJ, Martinelli E. Samer S, et al. Among authors: cicala c. JCI Insight. 2023 Nov 22;8(22):e176882. doi: 10.1172/jci.insight.176882. JCI Insight. 2023. PMID: 37991025 Free PMC article. No abstract available.
197 results