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CXCL9 recombinant adeno-associated virus (AAV) virotherapy sensitizes glioblastoma (GBM) to anti-PD-1 immune checkpoint blockade.
von Roemeling C, Yegorov O, Yang C, Klippel K, Russell R, Trivedi V, Bhatia A, Doonan B, Carpenter S, Ryu D, Grippen A, Futch H, Ran Y, Hoang-Minh L, Weidert F, Golde T, Mitchell D. von Roemeling C, et al. Among authors: futch h. Res Sq [Preprint]. 2023 Nov 14:rs.3.rs-3463730. doi: 10.21203/rs.3.rs-3463730/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Jul 12;15(1):5871. doi: 10.1038/s41467-024-49989-1 PMID: 38014191 Free PMC article. Updated. Preprint.
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.
Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, Janus C, Chakrabarty P, Judge AR, Brusko TM, de Kloet AD, Krause EG, Golde TE. Futch HS, et al. J Exp Med. 2019 Nov 4;216(11):2479-2491. doi: 10.1084/jem.20190430. Epub 2019 Aug 29. J Exp Med. 2019. PMID: 31467037 Free PMC article.
Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade.
von Roemeling CA, Patel JA, Carpenter SL, Yegorov O, Yang C, Bhatia A, Doonan BP, Russell R, Trivedi VS, Klippel K, Ryu DH, Grippin A, Futch HS, Ran Y, Hoang-Minh LB, Weidert FL, Golde TE, Mitchell DA. von Roemeling CA, et al. Among authors: futch hs. Nat Commun. 2024 Jul 12;15(1):5871. doi: 10.1038/s41467-024-49989-1. Nat Commun. 2024. PMID: 38997283 Free PMC article.
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS.
Goodwin MS, Croft CL, Futch HS, Ryu D, Ceballos-Diaz C, Liu X, Paterno G, Mejia C, Deng D, Menezes K, Londono L, Arjona K, Parianos M, Truong V, Rostonics E, Hernandez A, Boye SL, Boye SE, Levites Y, Cruz PE, Golde TE. Goodwin MS, et al. Among authors: futch hs. Mol Neurodegener. 2020 Mar 2;15(1):15. doi: 10.1186/s13024-020-00361-z. Mol Neurodegener. 2020. PMID: 32122372 Free PMC article.
Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts.
Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, Borchelt DR. Moore BD, et al. Among authors: futch hs. Free Neuropathol. 2022 Jan 11;3(9):3-9. doi: 10.17879/freeneuropathology-2022-3766. Epub 2022 Mar 23. Free Neuropathol. 2022. PMID: 35494163 Free PMC article.
Differential connexin function enhances self-renewal in glioblastoma.
Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, Sinyuk M, Otvos B, Brunet S, Flavahan WA, Hubert CG, Goan W, Hale JS, Alvarado AG, Zhang A, Rohaus M, Oli M, Vedam-Mai V, Fortin JM, Futch HS, Griffith B, Wu Q, Xia CH, Gong X, Ahluwalia MS, Rich JN, Reynolds BA, Lathia JD. Hitomi M, et al. Cell Rep. 2015 May 19;11(7):1031-42. doi: 10.1016/j.celrep.2015.04.021. Epub 2015 May 7. Cell Rep. 2015. PMID: 25959821 Free PMC article.
Obesity and STING1 genotype associate with 23-valent pneumococcal vaccination efficacy.
Sebastian M, Hsiao CJ, Futch HS, Eisinger RS, Dumeny L, Patel S, Gobena M, Katikaneni DS, Cohen J, Carpenter AM, Spiryda L, Heldermon CD, Jin L, Brantly ML. Sebastian M, et al. Among authors: futch hs. JCI Insight. 2020 May 7;5(9):e136141. doi: 10.1172/jci.insight.136141. JCI Insight. 2020. PMID: 32376795 Free PMC article.
18 results