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Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.
Kay KE, Lee J, Hong ES, Beilis J, Dayal S, Wesley E, Mitchell S, Wang SZ, Silver DJ, Volovetz J, Johnson S, McGraw M, Grabowski MM, Lu T, Freytag L, Narayana V, Freytag S, Best SA, Whittle JR, Wang Z, Reizes O, Yu JS, Hazen SL, Brown JM, Bayik D, Lathia JD. Kay KE, et al. Among authors: lee j. bioRxiv [Preprint]. 2023 Nov 16:2023.11.14.567048. doi: 10.1101/2023.11.14.567048. bioRxiv. 2023. Update in: J Clin Invest. 2024 Nov 19:e177824. doi: 10.1172/JCI177824 PMID: 38014234 Free PMC article. Updated. Preprint.
Sex Differences in Glioblastoma Immunotherapy Response.
Lee J, Kay K, Troike K, Ahluwalia MS, Lathia JD. Lee J, et al. Neuromolecular Med. 2022 Mar;24(1):50-55. doi: 10.1007/s12017-021-08659-x. Epub 2021 Apr 17. Neuromolecular Med. 2022. PMID: 33864598 Review.
Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
Bayik D, Bartels CF, Lovrenert K, Watson DC, Zhang D, Kay K, Lee J, Lauko A, Johnson S, Lo A, Silver DJ, McGraw M, Grabowski M, Mohammadi AM, Veglia F, Fan Y, Vogelbaum MA, Scacheri P, Lathia JD. Bayik D, et al. Among authors: lee j. Cancer Res. 2022 Nov 15;82(22):4274-4287. doi: 10.1158/0008-5472.CAN-21-3840. Cancer Res. 2022. PMID: 36126163 Free PMC article.
Spatial immunosampling of MRI-defined glioblastoma regions reveals immunologic fingerprint of non-contrast enhancing, infiltrative tumor margins.
Grabowski MM, Watson DC, Chung K, Lee J, Bayik D, Lauko A, Alban T, Melenhorst JJ, Chan T, Lathia JD, Ahluwalia MS, Mohammadi AM. Grabowski MM, et al. Among authors: lee j. medRxiv [Preprint]. 2023 Mar 9:2023.03.09.23285970. doi: 10.1101/2023.03.09.23285970. medRxiv. 2023. PMID: 36945620 Free PMC article. Preprint.
147,667 results
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