Sprang S - Search Results

1

The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Gα chaperone and GEF Ric-8A.

Muñoz-Reyes D, McClelland LJ, Arroyo-Urea S, Sánchez-Yepes S, Sabín J, Pérez-Suárez S, Menendez M, Mansilla A, García-Nafría J, Sprang S, Sanchez-Barrena MJ. Muñoz-Reyes D, et al. Among authors: sprang s. Elife. 2023 Nov 29;12:e86151. doi: 10.7554/eLife.86151. Elife. 2023. PMID: 38018500 Free PMC article.

2

Application of sulfur SAD to small crystals with a large asymmetric unit and anomalous substructure.

Mou TC, Zeng B, Doukov TI, Sprang SR. Mou TC, et al. Among authors: sprang sr. Acta Crystallogr D Struct Biol. 2022 Aug 1;78(Pt 8):1021-1031. doi: 10.1107/S2059798322005848. Epub 2022 Jul 14. Acta Crystallogr D Struct Biol. 2022. PMID: 35916226 Free PMC article.

3

The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a).

Kerchner KM, Mou TC, Sun Y, Rusnac DV, Sprang SR, Briknarová K. Kerchner KM, et al. Among authors: sprang sr. J Struct Biol X. 2021 Jun 25;5:100050. doi: 10.1016/j.yjsbx.2021.100050. eCollection 2021. J Struct Biol X. 2021. PMID: 34278292 Free PMC article.

4

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1.

McClelland LJ, Zhang K, Mou TC, Johnston J, Yates-Hansen C, Li S, Thomas CJ, Doukov TI, Triest S, Wohlkonig A, Tall GG, Steyaert J, Chiu W, Sprang SR. McClelland LJ, et al. Among authors: sprang sr. Nat Commun. 2020 Feb 26;11(1):1077. doi: 10.1038/s41467-020-14943-4. Nat Commun. 2020. PMID: 32103024 Free PMC article.

5

Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A.

Zeng B, Mou TC, Doukov TI, Steiner A, Yu W, Papasergi-Scott M, Tall GG, Hagn F, Sprang SR. Zeng B, et al. Among authors: sprang sr. Structure. 2019 Jul 2;27(7):1137-1147.e5. doi: 10.1016/j.str.2019.04.013. Epub 2019 May 30. Structure. 2019. PMID: 31155309 Free PMC article.

6

Atypical activation of the G protein Gα_q by the oncogenic mutation Q209P.

Maziarz M, Leyme A, Marivin A, Luebbers A, Patel PP, Chen Z, Sprang SR, Garcia-Marcos M. Maziarz M, et al. Among authors: sprang sr. J Biol Chem. 2018 Dec 21;293(51):19586-19599. doi: 10.1074/jbc.RA118.005291. Epub 2018 Oct 23. J Biol Chem. 2018. PMID: 30352874 Free PMC article.

7

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene.

Stump S, Mou TC, Sprang SR, Natale NR, Beall HD. Stump S, et al. Among authors: sprang sr. PLoS One. 2018 Oct 12;13(10):e0205584. doi: 10.1371/journal.pone.0205584. eCollection 2018. PLoS One. 2018. PMID: 30312328 Free PMC article.

8

Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα.

Kant R, Zeng B, Thomas CJ, Bothner B, Sprang SR. Kant R, et al. Among authors: sprang sr. Elife. 2016 Dec 23;5:e19238. doi: 10.7554/eLife.19238. Elife. 2016. PMID: 28008853 Free PMC article.

9

Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons.

McClelland LJ, Steele HB, Whitby FG, Mou TC, Holley D, Ross JB, Sprang SR, Bowler BE. McClelland LJ, et al. Among authors: sprang sr. J Am Chem Soc. 2016 Dec 28;138(51):16770-16778. doi: 10.1021/jacs.6b10745. Epub 2016 Dec 19. J Am Chem Soc. 2016. PMID: 27990813 Free PMC article.

10

Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.

Yi F, Mou TC, Dorsett KN, Volkmann RA, Menniti FS, Sprang SR, Hansen KB. Yi F, et al. Among authors: sprang sr. Neuron. 2016 Sep 21;91(6):1316-1329. doi: 10.1016/j.neuron.2016.08.014. Epub 2016 Sep 8. Neuron. 2016. PMID: 27618671 Free PMC article.

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