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Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations.
Castiello MC, Di Verniere M, Draghici E, Fontana E, Penna S, Sereni L, Zecchillo A, Minuta D, Uva P, Zahn M, Gil-Farina I, Annoni A, Iaia S, Ott de Bruin LM, Notarangelo LD, Pike-Overzet K, Staal FJT, Villa A, Capo V. Castiello MC, et al. Among authors: staal fjt. Front Immunol. 2023 Nov 13;14:1268620. doi: 10.3389/fimmu.2023.1268620. eCollection 2023. Front Immunol. 2023. PMID: 38022635 Free PMC article.
Advances in gene therapy for inborn errors of immunity.
Ott de Bruin LM, Lankester AC, Staal FJT. Ott de Bruin LM, et al. Among authors: staal fjt. Curr Opin Allergy Clin Immunol. 2023 Dec 1;23(6):467-477. doi: 10.1097/ACI.0000000000000952. Epub 2023 Oct 13. Curr Opin Allergy Clin Immunol. 2023. PMID: 37846903 Free PMC article. Review.
Tagged IDS causes efficient and engraftment-independent prevention of brain pathology during lentiviral gene therapy for Mucopolysaccharidosis type II.
Catalano F, Vlaar EC, Katsavelis D, Dammou Z, Huizer TF, van den Bosch JC, Hoogeveen-Westerveld M, van den Hout HJMP, Oussoren E, Ruijter GJG, Schaaf G, Pike-Overzet K, Staal FJT, van der Ploeg AT, Pijnappel WWMP. Catalano F, et al. Among authors: staal fjt. Mol Ther Methods Clin Dev. 2023 Nov 2;31:101149. doi: 10.1016/j.omtm.2023.101149. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38033460 Free PMC article.
European Society for Immunodeficiencies guidelines for the management of patients with congenital athymia.
Kreins AY, Dhalla F, Flinn AM, Howley E, Ekwall O, Villa A, Staal FJT, Anderson G, Gennery AR, Holländer GA, Davies EG; European Society for Immunodeficiencies Clinical Working Party. Kreins AY, et al. Among authors: staal fjt. J Allergy Clin Immunol. 2024 Dec;154(6):1391-1408. doi: 10.1016/j.jaci.2024.07.031. Epub 2024 Sep 18. J Allergy Clin Immunol. 2024. PMID: 39303894 Free article. Review.
Lentiviral Gene Therapy for Mucopolysaccharidosis II with Tagged Iduronate 2-Sulfatase Prevents Life-Threatening Pathology in Peripheral Tissues But Fails to Correct Cartilage.
Catalano F, Vlaar EC, Dammou Z, Katsavelis D, Huizer TF, Zundo G, Hoogeveen-Westerveld M, Oussoren E, van den Hout HJMP, Schaaf G, Pike-Overzet K, Staal FJT, van der Ploeg AT, Pijnappel WWMP. Catalano F, et al. Among authors: staal fjt. Hum Gene Ther. 2024 Apr;35(7-8):256-268. doi: 10.1089/hum.2023.177. Epub 2024 Feb 2. Hum Gene Ther. 2024. PMID: 38085235 Free PMC article.
Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.
Mbow M, Hoving D, Cisse M, Diallo I, Honkpehedji YJ, Huisman W, Pothast CR, Jongsma MLM, König MH, de Kroon AC, Linh LTK, Azimi S, Tak T, Kruize YCM, Kurniawan F, Dia YA, Zhang JLH, Prins C, Roukens AHE, de Vries JJC, Wammes LJ, Smits HH, Adegnika AA, Zlei M, Kuijpers TW, Wieske L, Dieye A, Mboup S, Kremsner PG, Eftimov F, Velavan TP, Berlin I, Heemskerk MHM, Yazdanbakhsh M, Jochems SP; BEAT-COVID consortium; COVID-19 Leiden University Medical Center study team. Mbow M, et al. Lancet Microbe. 2024 Dec 13:100942. doi: 10.1016/j.lanmic.2024.07.005. Online ahead of print. Lancet Microbe. 2024. PMID: 39708825 Free article.
Driving CAR-T cells toward solid lung tumors.
Staal FJT, Avila-Moreno F. Staal FJT, et al. Mol Ther Oncol. 2024 Feb 7;32(1):200764. doi: 10.1016/j.omton.2024.200764. eCollection 2024 Mar 21. Mol Ther Oncol. 2024. PMID: 38596284 Free PMC article. No abstract available.
Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease.
van Meijgaarden KE, van Veen S, Tsonaka R, Ruibal P, Roukens AHE, Arbous SM, Manniën J, Cannegieter SC, Ottenhoff THM, Joosten SA; BEAT-COVID group; COVID-19 LUMC group. van Meijgaarden KE, et al. Sci Rep. 2024 Jun 5;14(1):12882. doi: 10.1038/s41598-024-63586-8. Sci Rep. 2024. PMID: 38839796 Free PMC article.
160 results