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Page 1
Blood transcriptomic signature in type-2 biomarker-low severe asthma and asthma control.
Zeng X, Qing J, Li CM, Lu J, Yamawaki T, Hsu YH, Vander Lugt B, Hsu H, Busby J, McDowell PJ, Jackson DJ, Djukanovic R, Matthews JG, Arron JR, Bradding P, Brightling CE, Chaudhuri R, Choy DF, Cowan D, Fowler SJ, Hardman TC, Harrison T, Howarth P, Lordan J, Mansur AH, Menzies-Gow A, Pavord ID, Walker S, Woodcock A, Heaney LG; investigators for the UK MRC Refractory Asthma Stratification Program (RASP-UK). Zeng X, et al. Among authors: hardman tc. J Allergy Clin Immunol. 2023 Oct;152(4):876-886. doi: 10.1016/j.jaci.2023.05.023. Epub 2023 Jun 12. J Allergy Clin Immunol. 2023. PMID: 37315813 Free article. Clinical Trial.
A Randomized Trial of a Composite T2-Biomarker Strategy Adjusting Corticosteroid Treatment in Severe Asthma: A Post Hoc Analysis by Sex.
Eastwood MC, Busby J, Jackson DJ, Pavord ID, Hanratty CE, Djukanovic R, Woodcock A, Walker S, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan D, Mansur AH, Fowler SJ, Howarth P, Lordan J, Menzies-Gow A, Harrison T, Robinson DS, Holweg CTJ, Matthews JG, Heaney LG; Refractory Asthma Stratification Programme (UK) Investigators. Eastwood MC, et al. Among authors: hardman tc. J Allergy Clin Immunol Pract. 2023 Apr;11(4):1233-1242.e5. doi: 10.1016/j.jaip.2022.12.019. Epub 2023 Jan 5. J Allergy Clin Immunol Pract. 2023. PMID: 36621603 Free article. Clinical Trial.
The future of clinical trials and drug development: 2050.
Hardman TC, Aitchison R, Scaife R, Edwards J, Slater G. Hardman TC, et al. Drugs Context. 2023 Jun 8;12:2023-2-2. doi: 10.7573/dic.2023-2-2. eCollection 2023. Drugs Context. 2023. PMID: 37313038 Free PMC article.
Exacerbation Profile and Risk Factors in a Type-2-Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes.
McDowell PJ, Busby J, Hanratty CE, Djukanovic R, Woodcock A, Walker S, Hardman TC, Arron JR, Choy DF, Bradding P, Brightling CE, Chaudhuri R, Cowan D, Mansur AH, Fowler SJ, Diver SE, Howarth P, Lordan J, Menzies-Gow A, Harrison T, Robinson DS, Holweg CTJ, Matthews JG, Pavord ID, Heaney LG. McDowell PJ, et al. Among authors: hardman tc. Am J Respir Crit Care Med. 2022 Sep 1;206(5):545-553. doi: 10.1164/rccm.202201-0129OC. Am J Respir Crit Care Med. 2022. PMID: 35549845 Free PMC article. Clinical Trial.
Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma.
Busby J, Matthews JG, Chaudhuri R, Pavord ID, Hardman TC, Arron JR, Bradding P, Brightling CE, Choy DF, Cowan DC, Djukanovic R, Hanratty CE, Harrison TW, Holweg CT, Howarth PH, Fowler SJ, Lordan JL, Mansur AH, Menzies-Gow A, Niven RM, Robinson DS, Walker SM, Woodcock A, Heaney LG; investigators for the MRC Refractory Asthma Stratification Programme. Busby J, et al. Among authors: hardman tc. Eur Respir J. 2021 Sep 24;59(4):2100768. doi: 10.1183/13993003.00768-2021. Print 2022 Apr. Eur Respir J. 2021. PMID: 34561291 Free PMC article. Clinical Trial.
A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts.
Gomez-Cabrero D, Walter S, Abugessaisa I, Miñambres-Herraiz R, Palomares LB, Butcher L, Erusalimsky JD, Garcia-Garcia FJ, Carnicero J, Hardman TC, Mischak H, Zürbig P, Hackl M, Grillari J, Fiorillo E, Cucca F, Cesari M, Carrie I, Colpo M, Bandinelli S, Feart C, Peres K, Dartigues JF, Helmer C, Viña J, Olaso G, García-Palmero I, Martínez JG, Jansen-Dürr P, Grune T, Weber D, Lippi G, Bonaguri C, Sinclair AJ, Tegner J, Rodriguez-Mañas L; FRAILOMIC initiative. Gomez-Cabrero D, et al. Among authors: hardman tc. Geroscience. 2021 Jun;43(3):1317-1329. doi: 10.1007/s11357-021-00334-0. Epub 2021 Feb 18. Geroscience. 2021. PMID: 33599920 Free PMC article.
The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting October 2019: Impending Change, Innovation, and Future Challenges.
Khan S, Albayaty M, Bush J, Cheriyan J, Cromie A, Koch A, Hammond M, Mair S, Lorch U, Stringer S, Taubel J, Hardman TC. Khan S, et al. Among authors: hardman tc. Front Pharmacol. 2020 Nov 19;11:580560. doi: 10.3389/fphar.2020.580560. eCollection 2020. Front Pharmacol. 2020. PMID: 33364955 Free PMC article.
51 results