Smalley KSM - Search Results

1

HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.

Emmons MF, Bennett RL, Riva A, Gupta K, Carvalho LADC, Zhang C, Macaulay R, Dupéré-Richér D, Fang B, Seto E, Koomen JM, Li J, Chen YA, Forsyth PA, Licht JD, Smalley KSM. Emmons MF, et al. Among authors: smalley ksm. Nat Commun. 2023 Nov 29;14(1):7759. doi: 10.1038/s41467-023-43519-1. Nat Commun. 2023. PMID: 38030596 Free PMC article.

2

Methods for investigation of targeted kinase inhibitor therapy using chemical proteomics and phosphorylation profiling.

Fang B, Haura EB, Smalley KS, Eschrich SA, Koomen JM. Fang B, et al. Biochem Pharmacol. 2010 Sep 1;80(5):739-47. doi: 10.1016/j.bcp.2010.03.027. Epub 2010 Mar 31. Biochem Pharmacol. 2010. PMID: 20361944 Free PMC article. Review.

3

PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression.

Paraiso KH, Xiang Y, Rebecca VW, Abel EV, Chen YA, Munko AC, Wood E, Fedorenko IV, Sondak VK, Anderson AR, Ribas A, Palma MD, Nathanson KL, Koomen JM, Messina JL, Smalley KS. Paraiso KH, et al. Cancer Res. 2011 Apr 1;71(7):2750-60. doi: 10.1158/0008-5472.CAN-10-2954. Epub 2011 Feb 11. Cancer Res. 2011. PMID: 21317224 Free PMC article.

4

Using quantitative proteomic analysis to understand genotype specific intrinsic drug resistance in melanoma.

Koomen JM, Smalley KS. Koomen JM, et al. Oncotarget. 2011 Apr;2(4):329-35. doi: 10.18632/oncotarget.263. Oncotarget. 2011. PMID: 21505227 Free PMC article. Review.

5

A database of reaction monitoring mass spectrometry assays for elucidating therapeutic response in cancer.

Remily-Wood ER, Liu RZ, Xiang Y, Chen Y, Thomas CE, Rajyaguru N, Kaufman LM, Ochoa JE, Hazlehurst L, Pinilla-Ibarz J, Lancet J, Zhang G, Haura E, Shibata D, Yeatman T, Smalley KS, Dalton WS, Huang E, Scott E, Bloom GC, Eschrich SA, Koomen JM. Remily-Wood ER, et al. Proteomics Clin Appl. 2011 Aug;5(7-8):383-96. doi: 10.1002/prca.201000115. Epub 2011 Jun 8. Proteomics Clin Appl. 2011. PMID: 21656910 Free PMC article.

6

The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.

Paraiso KH, Haarberg HE, Wood E, Rebecca VW, Chen YA, Xiang Y, Ribas A, Lo RS, Weber JS, Sondak VK, John JK, Sarnaik AA, Koomen JM, Smalley KS. Paraiso KH, et al. Clin Cancer Res. 2012 May 1;18(9):2502-14. doi: 10.1158/1078-0432.CCR-11-2612. Epub 2012 Feb 20. Clin Cancer Res. 2012. PMID: 22351686 Free PMC article.

7

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation.

John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. John JK, et al. J Invest Dermatol. 2012 Dec;132(12):2818-27. doi: 10.1038/jid.2012.237. Epub 2012 Jul 19. J Invest Dermatol. 2012. PMID: 22810307 Free PMC article.

8

Inhibition of Wee1, AKT, and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS-mutant melanoma.

Haarberg HE, Paraiso KH, Wood E, Rebecca VW, Sondak VK, Koomen JM, Smalley KS. Haarberg HE, et al. Mol Cancer Ther. 2013 Jun;12(6):901-12. doi: 10.1158/1535-7163.MCT-12-1003. Epub 2013 Mar 28. Mol Cancer Ther. 2013. PMID: 23538902 Free PMC article.

9

Paradoxical oncogenesis--the long-term effects of BRAF inhibition in melanoma.

Gibney GT, Messina JL, Fedorenko IV, Sondak VK, Smalley KS. Gibney GT, et al. Nat Rev Clin Oncol. 2013 Jul;10(7):390-9. doi: 10.1038/nrclinonc.2013.83. Epub 2013 May 28. Nat Rev Clin Oncol. 2013. PMID: 23712190 Free PMC article. Review.

10

Novel treatments for melanoma brain metastases.

Kenchappa RS, Tran N, Rao NG, Smalley KS, Gibney GT, Sondak VK, Forsyth PA. Kenchappa RS, et al. Cancer Control. 2013 Oct;20(4):298-306. doi: 10.1177/107327481302000407. Cancer Control. 2013. PMID: 24077406 Free article. Review.

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