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Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data.
O'Donovan SD, Cavill R, Wimmenauer F, Lukas A, Stumm T, Smirnov E, Lenz M, Ertaylan G, Jennen DGJ, van Riel NAW, Driessens K, Peeters RLM, de Kok TMCM. O'Donovan SD, et al. Among authors: peeters rlm. PLoS One. 2023 Nov 30;18(11):e0292030. doi: 10.1371/journal.pone.0292030. eCollection 2023. PLoS One. 2023. PMID: 38032940 Free PMC article.
Use of deep learning methods to translate drug-induced gene expression changes from rat to human primary hepatocytes.
O'Donovan SD, Driessens K, Lopatta D, Wimmenauer F, Lukas A, Neeven J, Stumm T, Smirnov E, Lenz M, Ertaylan G, Jennen DGJ, van Riel NAW, Cavill R, Peeters RLM, de Kok TMCM. O'Donovan SD, et al. Among authors: peeters rlm. PLoS One. 2020 Aug 11;15(8):e0236392. doi: 10.1371/journal.pone.0236392. eCollection 2020. PLoS One. 2020. PMID: 32780735 Free PMC article.
A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data.
O'Donovan SD, Lenz M, Vink RG, Roumans NJT, de Kok TMCM, Mariman ECM, Peeters RLM, van Riel NAW, van Baak MA, Arts ICW. O'Donovan SD, et al. Among authors: peeters rlm. PLoS Comput Biol. 2019 Oct 3;15(10):e1007400. doi: 10.1371/journal.pcbi.1007400. eCollection 2019 Oct. PLoS Comput Biol. 2019. PMID: 31581241 Free PMC article.
Improved quantification of muscle insulin sensitivity using oral glucose tolerance test data: the MISI Calculator.
O'Donovan SD, Lenz M, Goossens GH, van der Kallen CJH, Eussen SJMP, Stehouwer CDA, van Greevenbroek MM, Schram MT, Sep SJ, Peeters RLM, Blaak EE, van Riel NAW, de Kok TMCM, Arts ICW. O'Donovan SD, et al. Among authors: peeters rlm. Sci Rep. 2019 Jun 28;9(1):9388. doi: 10.1038/s41598-019-45858-w. Sci Rep. 2019. PMID: 31253846 Free PMC article.
In Vivo Validation of Electrocardiographic Imaging.
Cluitmans MJM, Bonizzi P, Karel JMH, Das M, Kietselaer BLJH, de Jong MMJ, Prinzen FW, Peeters RLM, Westra RL, Volders PGA. Cluitmans MJM, et al. Among authors: peeters rlm. JACC Clin Electrophysiol. 2017 Mar;3(3):232-242. doi: 10.1016/j.jacep.2016.11.012. Epub 2017 Feb 1. JACC Clin Electrophysiol. 2017. PMID: 29759517 Free article.
17 results