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Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism.
Amorim R, Magalhães CC, Benfeito S, Cagide F, Tavares LC, Santos K, Sardão VA, Datta S, Cortopassi GA, Baldeiras I, Jones JG, Borges F, Oliveira PJ, Teixeira J. Amorim R, et al. Among authors: cagide f. Biochem Pharmacol. 2024 Jan;219:115953. doi: 10.1016/j.bcp.2023.115953. Epub 2023 Nov 29. Biochem Pharmacol. 2024. PMID: 38036191 Free article.
Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage.
Amorim R, Cagide F, Tavares LC, Simões RF, Soares P, Benfeito S, Baldeiras I, Jones JG, Borges F, Oliveira PJ, Teixeira J. Amorim R, et al. Among authors: cagide f. Free Radic Biol Med. 2022 Feb 1;179:119-132. doi: 10.1016/j.freeradbiomed.2021.12.304. Epub 2021 Dec 22. Free Radic Biol Med. 2022. PMID: 34954022
A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients.
Deus CM, Pereira SP, Cunha-Oliveira T, Teixeira J, Simões RF, Cagide F, Benfeito S, Borges F, Raimundo N, Oliveira PJ. Deus CM, et al. Among authors: cagide f. Redox Biol. 2021 Sep;45:102037. doi: 10.1016/j.redox.2021.102037. Epub 2021 Jun 8. Redox Biol. 2021. PMID: 34147843 Free PMC article.
52 results