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Page 1
The immunogenicity of an HIV-1 Gag conserved element DNA vaccine in people with HIV and receiving antiretroviral therapy.
Jacobson JM, Felber BK, Chen H, Pavlakis GN, Mullins JI, De Rosa SC, Kuritzkes DR, Tomaras GD, Kinslow J, Bao Y, Olefsky M, Rosati M, Bear J, Heptinstall JR, Zhang L, Sawant S, Hannaman D, Laird GM, Cyktor JC, Heath SL, Collier AC, Koletar SL, Taiwo BO, Tebas P, Wohl DA, Belaunzaran-Zamudio PF, McElrath MJ, Landay AL; ACTG 5369 Study Team. Jacobson JM, et al. Among authors: cyktor jc. AIDS. 2024 Jun 1;38(7):963-973. doi: 10.1097/QAD.0000000000003804. Epub 2023 Dec 1. AIDS. 2024. PMID: 38051788 Clinical Trial.
Selective Decay of Intact HIV-1 Proviral DNA on Antiretroviral Therapy.
Gandhi RT, Cyktor JC, Bosch RJ, Mar H, Laird GM, Martin A, Collier AC, Riddler SA, Macatangay BJ, Rinaldo CR, Eron JJ, Siliciano JD, McMahon DK, Mellors JW; AIDS Clinical Trials Group A5321 Team. Gandhi RT, et al. Among authors: cyktor jc. J Infect Dis. 2021 Feb 3;223(2):225-233. doi: 10.1093/infdis/jiaa532. J Infect Dis. 2021. PMID: 32823274 Free PMC article.
Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation.
Gandhi RT, McMahon DK, Bosch RJ, Lalama CM, Cyktor JC, Macatangay BJ, Rinaldo CR, Riddler SA, Hogg E, Godfrey C, Collier AC, Eron JJ, Mellors JW; ACTG A5321 Team. Gandhi RT, et al. Among authors: cyktor jc. PLoS Pathog. 2017 Apr 20;13(4):e1006285. doi: 10.1371/journal.ppat.1006285. eCollection 2017 Apr. PLoS Pathog. 2017. PMID: 28426825 Free PMC article.
Varied Patterns of Decay of Intact Human Immunodeficiency Virus Type 1 Proviruses Over 2 Decades of Antiretroviral Therapy.
Gandhi RT, Bosch RJ, Mar H, Laird GM, Halvas EK, Hovind L, Collier AC, Riddler SA, Martin A, Ritter K, McMahon DK, Eron JJ, Cyktor JC, Mellors JW; AIDS Clinical Trials Group A5321 Team. Gandhi RT, et al. Among authors: cyktor jc. J Infect Dis. 2023 Jun 15;227(12):1376-1380. doi: 10.1093/infdis/jiad039. J Infect Dis. 2023. PMID: 36763044 Free PMC article.
Brief Report: No Evidence for an Association Between Statin Use and Lower Biomarkers of HIV Persistence or Immune Activation/Inflammation During Effective ART.
Bedimo RJ, Mar H, Bosch RJ, Drechsler H, Cyktor JC, Macatangay BJC, Lalama C, Rinaldo C Jr, Collier A, Godfrey C, Hogg E, Hensel C, Eron JJ, Mcmahon DK, Mellors JW, Tebas P, Gandhi RT; A5321 Study Team. Bedimo RJ, et al. Among authors: cyktor jc. J Acquir Immune Defic Syndr. 2019 Oct 1;82(2):e27-e31. doi: 10.1097/QAI.0000000000002124. J Acquir Immune Defic Syndr. 2019. PMID: 31335587 Free PMC article.
T cells with high PD-1 expression are associated with lower HIV-specific immune responses despite long-term antiretroviral therapy.
Macatangay BJC, Gandhi RT, Jones RB, Mcmahon DK, Lalama CM, Bosch RJ, Cyktor JC, Thomas AS, Borowski L, Riddler SA, Hogg E, Stevenson E, Eron JJ, Mellors JW, Rinaldo CR; ACTG A5321 Team. Macatangay BJC, et al. Among authors: cyktor jc. AIDS. 2020 Jan 1;34(1):15-24. doi: 10.1097/QAD.0000000000002406. AIDS. 2020. PMID: 31634201 Free PMC article.
Persistent HIV-infected cells in cerebrospinal fluid are associated with poorer neurocognitive performance.
Spudich S, Robertson KR, Bosch RJ, Gandhi RT, Cyktor JC, Mar H, Macatangay BJ, Lalama CM, Rinaldo C, Collier AC, Godfrey C, Eron JJ, McMahon D, Jacobs JL, Koontz D, Hogg E, Vecchio A, Mellors JW. Spudich S, et al. Among authors: cyktor jc. J Clin Invest. 2019 Jul 15;129(8):3339-3346. doi: 10.1172/JCI127413. eCollection 2019 Jul 15. J Clin Invest. 2019. PMID: 31305262 Free PMC article. Clinical Trial.
No evidence that circulating HIV-specific immune responses contribute to persistent inflammation and immune activation in persons on long-term ART.
Ward AR, Thomas AS, Stevenson EM, Huang SH, Keating SM, Gandhi RT, McMahon DK, Bosch RJ, Macatangay BJ, Cyktor JC, Eron JJ, Mellors JW, Jones RB; ACTG A5321 Team. Ward AR, et al. Among authors: cyktor jc. AIDS. 2022 Oct 1;36(12):1617-1628. doi: 10.1097/QAD.0000000000003301. Epub 2022 Jun 22. AIDS. 2022. PMID: 35730388 Free PMC article.
Randomized Clinical Trial to Assess the Impact of the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01 on HIV-1 Persistence in Individuals on Effective ART.
Riddler SA, Zheng L, Durand CM, Ritz J, Koup RA, Ledgerwood J, Bailer RT, Koletar SL, Eron JJ, Keefer MC, Macatangay BJC, Cyktor JC, Mellors JW; AIDS Clinical Trials Group A5342 Protocol Team. Riddler SA, et al. Among authors: cyktor jc. Open Forum Infect Dis. 2018 Oct 20;5(10):ofy242. doi: 10.1093/ofid/ofy242. eCollection 2018 Oct. Open Forum Infect Dis. 2018. PMID: 30364428 Free PMC article.
44 results