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A tool for monitoring cell type-specific focused ultrasound neuromodulation and control of chronic epilepsy.
Murphy KR, Farrell JS, Gomez JL, Stedman QG, Li N, Leung SA, Good CH, Qiu Z, Firouzi K, Butts Pauly K, Khuri-Yakub BPT, Michaelides M, Soltesz I, de Lecea L. Murphy KR, et al. Among authors: de lecea l. Proc Natl Acad Sci U S A. 2022 Nov 16;119(46):e2206828119. doi: 10.1073/pnas.2206828119. Epub 2022 Nov 7. Proc Natl Acad Sci U S A. 2022. PMID: 36343238 Free PMC article.
Dorsomedial and preoptic hypothalamic circuits control torpor.
Yamaguchi H, Murphy KR, Fukatsu N, Sato K, Yamanaka A, de Lecea L. Yamaguchi H, et al. Among authors: de lecea l. Curr Biol. 2023 Dec 18;33(24):5381-5389.e4. doi: 10.1016/j.cub.2023.10.076. Epub 2023 Nov 21. Curr Biol. 2023. PMID: 37992720 Free article.
A cluster of neuropeptide S neurons regulates breathing and arousal.
Angelakos CC, Girven KS, Liu Y, Gonzalez OC, Murphy KR, Jennings KJ, Giardino WJ, Zweifel LS, Suko A, Palmiter RD, Clark SD, Krasnow MA, Bruchas MR, de Lecea L. Angelakos CC, et al. Among authors: de lecea l. Curr Biol. 2023 Dec 18;33(24):5439-5455.e7. doi: 10.1016/j.cub.2023.11.018. Epub 2023 Dec 5. Curr Biol. 2023. PMID: 38056461 Free PMC article.
Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology.
Murphy KR, Farrell JS, Bendig J, Mitra A, Luff C, Stelzer IA, Yamaguchi H, Angelakos CC, Choi M, Bian W, DiIanni T, Pujol EM, Matosevich N, Airan R, Gaudillière B, Konofagou EE, Butts-Pauly K, Soltesz I, de Lecea L. Murphy KR, et al. Among authors: de lecea l. Neuron. 2024 Oct 9;112(19):3252-3266.e5. doi: 10.1016/j.neuron.2024.07.002. Epub 2024 Jul 29. Neuron. 2024. PMID: 39079529
Hypocretin (Orexin) Replacement Therapies.
Seigneur E, de Lecea L. Seigneur E, et al. Among authors: de lecea l. Med Drug Discov. 2020 Dec;8:100070. doi: 10.1016/j.medidd.2020.100070. Epub 2020 Oct 17. Med Drug Discov. 2020. PMID: 38738170 Free PMC article.
Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity.
Yang D, Wang Y, Qi T, Zhang X, Shen L, Ma J, Pang Z, Lal NK, McClatchy DB, Seradj SH, Leung VH, Wang K, Xie Y, Polli FS, Maximov A, Gonzalez OC, de Lecea L, Cline HT, Augustine V, Yates JR 3rd, Ye L. Yang D, et al. Among authors: de lecea l. Neuron. 2024 Mar 20;112(6):959-971.e8. doi: 10.1016/j.neuron.2023.12.015. Epub 2024 Jan 23. Neuron. 2024. PMID: 38266644 Free article.
207 results