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Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E. Myers JW, et al. Among authors: shaikh z. bioRxiv [Preprint]. 2024 Nov 1:2024.10.28.620705. doi: 10.1101/2024.10.28.620705. bioRxiv. 2024. PMID: 39553975 Free PMC article. Preprint.
A Comparative Study of Ocular Surface Disease in Childhood Glaucoma.
Elhusseiny AM, Haseeb A, Eleiwa TK, Elfattah DA, Sadik N, Solyman O, Chauhan MZ, Shaikh Z, Elsaadani I, Elwehidy AS, Saeed HN. Elhusseiny AM, et al. Among authors: shaikh z. Cornea. 2024 Sep 20. doi: 10.1097/ICO.0000000000003684. Online ahead of print. Cornea. 2024. PMID: 39312704
A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress.
Katz JL, Geng Y, Billingham LK, Sadagopan NS, DeLay SL, Subbiah J, Chia TY, McManus G, Wei C, Wang H, Lin H, Silvers C, Boland LK, Wang S, Wan H, Hou D, Vázquez-Cervantes GI, Arjmandi T, Shaikh ZH, Zhang P, Ahmed AU, Tiek DM, Lee-Chang C, Chouchani ET, Miska J. Katz JL, et al. Among authors: shaikh zh. Sci Rep. 2024 Sep 20;14(1):21959. doi: 10.1038/s41598-024-73051-1. Sci Rep. 2024. PMID: 39304717 Free PMC article.
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis.
Pinette JA, Myers JW, Park WY, Bryant HG, Eddie AM, Wilson GA, Montufar C, Shaikh Z, Vue Z, Nunn ER, Bessho R, Cottam MA, Haase VH, Hinton AO, Spinelli JB, Cartailler JP, Zaganjor E. Pinette JA, et al. Among authors: shaikh z. J Lipid Res. 2024 Oct;65(10):100641. doi: 10.1016/j.jlr.2024.100641. Epub 2024 Sep 6. J Lipid Res. 2024. PMID: 39245323 Free article.
233 results