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Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease.
Qian X, Klatt S, Bennewitz K, Wohlfart DP, Lou B, Meng Y, Buettner M, Poschet G, Morgenstern J, Fleming T, Sticht C, Hausser I, Fleming I, Szendroedi J, Nawroth PP, Kroll J. Qian X, et al. Among authors: fleming t, fleming i. Adv Sci (Weinh). 2024 Jan;11(4):e2302325. doi: 10.1002/advs.202302325. Epub 2023 Dec 7. Adv Sci (Weinh). 2024. PMID: 38059818 Free PMC article.
Aging-dependent reduction in glyoxalase 1 delays wound healing.
Fleming TH, Theilen TM, Masania J, Wunderle M, Karimi J, Vittas S, Bernauer R, Bierhaus A, Rabbani N, Thornalley PJ, Kroll J, Tyedmers J, Nawrotzki R, Herzig S, Brownlee M, Nawroth PP. Fleming TH, et al. Gerontology. 2013;59(5):427-37. doi: 10.1159/000351628. Epub 2013 Jun 22. Gerontology. 2013. PMID: 23797271
Effect of metformin on methylglyoxal metabolism in patients with type 2 diabetes.
Kender Z, Fleming T, Kopf S, Torzsa P, Grolmusz V, Herzig S, Schleicher E, Rácz K, Reismann P, Nawroth PP. Kender Z, et al. Among authors: fleming t. Exp Clin Endocrinol Diabetes. 2014 May;122(5):316-9. doi: 10.1055/s-0034-1371818. Epub 2014 Apr 7. Exp Clin Endocrinol Diabetes. 2014. PMID: 24710646 Clinical Trial.
1,162 results