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Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Aksu M, Kumar P, Güttler T, Taxer W, Gregor K, Mußil B, Rymarenko O, Stegmann KM, Dickmanns A, Gerber S, Reineking W, Schulz C, Henneck T, Mohamed A, Pohlmann G, Ramazanoglu M, Mese K, Groß U, Ben-Yedidia T, Ovadia O, Fischer DW, Kamensky M, Reichman A, Baumgärtner W, von Köckritz-Blickwede M, Dobbelstein M, Görlich D. Aksu M, et al. Among authors: gorlich d. Antiviral Res. 2024 Jan;221:105778. doi: 10.1016/j.antiviral.2023.105778. Epub 2023 Dec 7. Antiviral Res. 2024. PMID: 38065245 Free article.
N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody.
Zibat A, Zhang X, Dickmanns A, Stegmann KM, Dobbelstein AW, Alachram H, Soliwoda R, Salinas G, Groß U, Görlich D, Kschischo M, Wollnik B, Dobbelstein M. Zibat A, et al. Among authors: gorlich d. iScience. 2023 Aug 30;26(10):107786. doi: 10.1016/j.isci.2023.107786. eCollection 2023 Oct 20. iScience. 2023. PMID: 37731621 Free PMC article.
BLOOD PROTEOMICS AND MULTIMODAL RISK PROFILING of human volunteers after incision injury: a translational study for advancing Personalized Pain Management After Surgery.
Segelcke D, Sondermann JR, Christin K, Pradier B, Görlich D, Fobker M, Vollert J, Zahn PK, Schmidt M, Pogatzki-Zahn EM. Segelcke D, et al. Among authors: gorlich d. Pharmacol Res. 2025 Jan 3:107580. doi: 10.1016/j.phrs.2025.107580. Online ahead of print. Pharmacol Res. 2025. PMID: 39756555 Free article.
Improving risk stratification for 2022 European LeukemiaNet favorable-risk patients with acute myeloid leukemia.
Archer KJ, Fu H, Mrózek K, Nicolet D, Mims AS, Uy GL, Stock W, Byrd JC, Hiddemann W, Metzeler KH, Rausch C, Krug U, Sauerland C, Görlich D, Berdel WE, Woermann BJ, Braess J, Spiekermann K, Herold T, Eisfeld AK. Archer KJ, et al. Among authors: gorlich d. Innovation (Camb). 2024 Oct 21;5(6):100719. doi: 10.1016/j.xinn.2024.100719. eCollection 2024 Nov 4. Innovation (Camb). 2024. PMID: 39529956 Free PMC article.
Making acute ischemic stroke thrombi visible in MRI imaging.
Velasco Gonzalez A, Buerke B, Görlich D, Sauerland C, Fobker M, Jeibmann A, Heindel W, Faldum A, Paulus W, Kugel H. Velasco Gonzalez A, et al. Among authors: gorlich d. Sci Rep. 2024 May 29;14(1):12325. doi: 10.1038/s41598-024-62985-1. Sci Rep. 2024. PMID: 38811621 Free PMC article.
Ganglioside SSEA-4 in Ewing sarcoma marks a tumor cell population with aggressive features and is a potential cell-surface immune target.
Jamitzky S, Altvater B, Krekeler C, Hoen L, Brandes C, Ebbinghaus J, Richter L, Kosel L, Ochs L, Farwick N, Urban K, Kluge L, Bücker L, Görlich D, Johnston ICD, Pfeifer R, Hartmann W, Rossig C, Kailayangiri S. Jamitzky S, et al. Among authors: gorlich d. Sci Rep. 2024 May 24;14(1):11935. doi: 10.1038/s41598-024-62849-8. Sci Rep. 2024. PMID: 38789477 Free PMC article.
Exploring the relationship between embolic acute stroke distribution and supra-aortic vessel patency: key findings from an in vitro model study.
Velasco Gonzalez A, Sauerland C, Görlich D, Ortega-Quintanilla J, Jeibmann A, Faldum A, Paulus W, Heindel W, Buerke B. Velasco Gonzalez A, et al. Among authors: gorlich d. Stroke Vasc Neurol. 2024 May 23:svn-2023-003024. doi: 10.1136/svn-2023-003024. Online ahead of print. Stroke Vasc Neurol. 2024. PMID: 38782495 Free article.
275 results