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Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot.
Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Davis RJ, Del Toro DE, Dirain ML, Dram A, Hale LO, Heidarian M, Kim CY, Kucaba TA, Lanz JP, McCray AE, Meszaros S, Miles S, Nelson CR, Rocha IL, Silva EE, Ungaro RF, Walton AH, Xu J, Zeumer-Spataro L, Drewry AM, Liang M, Bible LE, Loftus TJ, Turnbull IR, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EL, et al. Among authors: kucaba ta. JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785. JCI Insight. 2024. PMID: 38100268 Free PMC article.
Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γELISpot: A Multicenter, Prospective Observational Study.
Barrios EA, Mazer MB, McGonagill P, Bergmann CB, Goodman MD, Gould R, Rao M, Polcz V, Davis R, Del Toro D, Dirain M, Dram A, Hale L, Heidarian M, Kucaba TA, Lanz JP, McCray A, Meszaros S, Miles S, Nelson C, Rocha I, Silva EE, Ungaro R, Walton A, Xu J, Zeumer-Spataro L, Drewry A, Liang M, Bible LE, Loftus T, Turnbull I, Efron PA, Remy KE, Brakenridge S, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Barrios EA, et al. Among authors: kucaba ta. medRxiv [Preprint]. 2023 Sep 24:2023.09.13.23295360. doi: 10.1101/2023.09.13.23295360. medRxiv. 2023. Update in: JCI Insight. 2024 Jan 23;9(2):e175785. doi: 10.1172/jci.insight.175785 PMID: 37745385 Free PMC article. Updated. Preprint.
CD115+ monocytes protect microbially experienced mice against E. coli-induced sepsis.
Martin MD, Skon-Hegg C, Kim CY, Xu J, Kucaba TA, Swanson W, Pierson MJ, Williams JW, Badovinac VP, Shen SS, Ingersoll MA, Griffith TS. Martin MD, et al. Among authors: kucaba ta. Cell Rep. 2023 Nov 28;42(11):113345. doi: 10.1016/j.celrep.2023.113345. Epub 2023 Oct 28. Cell Rep. 2023. PMID: 38111515 Free PMC article.
Development and optimization of a diluted whole blood ELISpot assay to test immune function.
Ungaro RF, Xu J, Kucaba TA, Rao M, Bergmann CB, Brakenridge SC, Efron PA, Goodman MD, Gould RW, Hotchkiss RS, Liang M, Mazer MB, McGonagill PW, Moldawer LL, Remy KE, Turnbull IR, Caldwell CC, Badovinac VP, Griffith TS. Ungaro RF, et al. Among authors: kucaba ta. J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743. Epub 2024 Aug 13. J Immunol Methods. 2024. PMID: 39147231 Free article.
Surviving septic patients endotyped with a functional assay demonstrate active immune responses.
Price AD, Becker ER, Barrios EL, Mazer MB, McGonagill PW, Bergmann CB, Goodman MD, Gould RW, Rao M, Polcz VE, Kucaba TA, Walton AH, Miles S, Xu J, Liang M, Loftus TJ, Efron PA, Remy KE, Brakenridge SC, Badovinac VP, Griffith TS, Moldawer LL, Hotchkiss RS, Caldwell CC. Price AD, et al. Among authors: kucaba ta. Front Immunol. 2024 Oct 14;15:1418613. doi: 10.3389/fimmu.2024.1418613. eCollection 2024. Front Immunol. 2024. PMID: 39469706 Free PMC article.
Polymicrobial Sepsis Impairs Antigen-Specific Memory CD4 T Cell-Mediated Immunity.
Sjaastad FV, Kucaba TA, Dileepan T, Swanson W, Dail C, Cabrera-Perez J, Murphy KA, Badovinac VP, Griffith TS. Sjaastad FV, et al. Among authors: kucaba ta. Front Immunol. 2020 Aug 12;11:1786. doi: 10.3389/fimmu.2020.01786. eCollection 2020. Front Immunol. 2020. PMID: 32903436 Free PMC article.
41 results