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The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.
Goyette MA, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault MP, Johnson RM, Carmeliet P, Basik M, Gaboury L, Muller WJ, Park M, Roux PP, Gratton JP, Côté JF. Goyette MA, et al. Among authors: savage p. Cell Rep. 2023 Dec 26;42(12):113604. doi: 10.1016/j.celrep.2023.113604. Epub 2023 Dec 14. Cell Rep. 2023. PMID: 38100352 Free article. No abstract available.
A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.
Savage P, Blanchet-Cohen A, Revil T, Badescu D, Saleh SMI, Wang YC, Zuo D, Liu L, Bertos NR, Munoz-Ramos V, Basik M, Petrecca K, Asselah J, Meterissian S, Guiot MC, Omeroglu A, Kleinman CL, Park M, Ragoussis J. Savage P, et al. Cell Rep. 2017 Oct 31;21(5):1140-1149. doi: 10.1016/j.celrep.2017.10.015. Cell Rep. 2017. PMID: 29091754 Free article.
The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.
Goyette MA, Duhamel S, Aubert L, Pelletier A, Savage P, Thibault MP, Johnson RM, Carmeliet P, Basik M, Gaboury L, Muller WJ, Park M, Roux PP, Gratton JP, Côté JF. Goyette MA, et al. Among authors: savage p. Cell Rep. 2018 May 1;23(5):1476-1490. doi: 10.1016/j.celrep.2018.04.019. Cell Rep. 2018. PMID: 29719259 Free article.
Co-dependency for MET and FGFR1 in basal triple-negative breast cancers.
Sung VYC, Knight JF, Johnson RM, Stern YE, Saleh SM, Savage P, Monast A, Zuo D, Duhamel S, Park M. Sung VYC, et al. Among authors: savage p. NPJ Breast Cancer. 2021 Mar 26;7(1):36. doi: 10.1038/s41523-021-00238-4. NPJ Breast Cancer. 2021. PMID: 33772015 Free PMC article.
ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer.
Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V. Deblois G, et al. Among authors: savage p. Nat Commun. 2016 Jul 12;7:12156. doi: 10.1038/ncomms12156. Nat Commun. 2016. PMID: 27402251 Free PMC article.
An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis.
Smith HW, Hirukawa A, Sanguin-Gendreau V, Nandi I, Dufour CR, Zuo D, Tandoc K, Leibovitch M, Singh S, Rennhack JP, Swiatnicki M, Lavoie C, Papavasiliou V, Temps C, Carragher NO, Unciti-Broceta A, Savage P, Basik M, van Hoef V, Larsson O, Cooper CL, Vargas Calderon AC, Beith J, Millar E, Selinger C, Giguère V, Park M, Harris LN, Varadan V, Andrechek ER, O'Toole SA, Topisirovic I, Muller WJ. Smith HW, et al. Among authors: savage p. Nat Commun. 2019 Jul 1;10(1):2901. doi: 10.1038/s41467-019-10681-4. Nat Commun. 2019. PMID: 31263101 Free PMC article.
Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression.
Nandi I, Smith HW, Sanguin-Gendreau V, Ji L, Pacis A, Papavasiliou V, Zuo D, Nam S, Attalla SS, Kim SH, Lusson S, Kuasne H, Fortier AM, Savage P, Martinez Ramirez C, Park M, Katzenellenbogen JA, Katzenellenbogen BS, Muller WJ. Nandi I, et al. Among authors: savage p. J Clin Invest. 2023 Apr 3;133(7):e162324. doi: 10.1172/JCI162324. J Clin Invest. 2023. PMID: 36795481 Free PMC article.
Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes.
Dankner M, Maritan SM, Priego N, Kruck G, Nkili-Meyong A, Nadaf J, Zhuang R, Annis MG, Zuo D, Nowakowski A, Biondini M, Kiepas A, Mourcos C, Le P, Charron F, Inglebert Y, Savage P, Théret L, Guiot MC, McKinney RA, Muller WJ, Park M, Valiente M, Petrecca K, Siegel PM. Dankner M, et al. Among authors: savage p. Neuro Oncol. 2024 Jun 3;26(6):1052-1066. doi: 10.1093/neuonc/noae013. Neuro Oncol. 2024. PMID: 38271182
Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis.
Jiang HY, Najmeh S, Martel G, MacFadden-Murphy E, Farias R, Savage P, Leone A, Roussel L, Cools-Lartigue J, Gowing S, Berube J, Giannias B, Bourdeau F, Chan CHF, Spicer JD, McClure R, Park M, Rousseau S, Ferri LE. Jiang HY, et al. Among authors: savage p. Protein Cell. 2020 Mar;11(3):187-201. doi: 10.1007/s13238-019-00687-5. Epub 2020 Jan 19. Protein Cell. 2020. PMID: 31956962 Free PMC article.
1,086 results