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MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R. Pomella S, et al. Among authors: alaggio r. Nat Commun. 2023 Dec 15;14(1):8373. doi: 10.1038/s41467-023-44130-0. Nat Commun. 2023. PMID: 38102140 Free PMC article.
Biological Role and Clinical Implications of MYOD1L122R Mutation in Rhabdomyosarcoma.
Di Carlo D, Chisholm J, Kelsey A, Alaggio R, Bisogno G, Minard-Colin V, Jenney M, Dávila Fajardo R, Merks JHM, Shipley JM, Selfe JL. Di Carlo D, et al. Among authors: alaggio r. Cancers (Basel). 2023 Mar 7;15(6):1644. doi: 10.3390/cancers15061644. Cancers (Basel). 2023. PMID: 36980529 Free PMC article. Review.
Intrathoracic synovial sarcoma with BRAF V600E mutation.
Russo I, Barresi S, Di Paolo PL, Di Ruscio V, Del Baldo G, Serra A, Vallese S, Miele E, Mastronuzzi A, Alaggio R, Ferrari A, Milano GM. Russo I, et al. Among authors: alaggio r. Oncotarget. 2023 Jul 7;14:703-708. doi: 10.18632/oncotarget.28475. Oncotarget. 2023. PMID: 37417899 Free PMC article.
Malignant peripheral nerve sheath tumor (MPNST) and MPNST-like entities are defined by a specific DNA methylation profile in pediatric and juvenile population.
Patrizi S, Miele E, Falcone L, Vallese S, Rossi S, Barresi S, Giovannoni I, Pedace L, Nardini C, Masier I, Abballe L, Cacchione A, Russo I, Di Giannatale A, Di Ruscio V, Salgado CM, Mastronuzzi A, Ciolfi A, Tartaglia M, Milano GM, Locatelli F, Alaggio R. Patrizi S, et al. Among authors: alaggio r. Clin Epigenetics. 2024 Jan 4;16(1):9. doi: 10.1186/s13148-023-01621-7. Clin Epigenetics. 2024. PMID: 38178234 Free PMC article.
Plasma-derived extracellular vesicles miR-335-5p as potential diagnostic biomarkers for fusion-positive rhabdomyosarcoma.
Di Paolo V, Paolini A, Galardi A, Gasparini P, De Cecco L, Colletti M, Lampis S, Raieli S, De Stefanis C, Miele E, Russo I, Di Ruscio V, Casanova M, Alaggio R, Masotti A, Milano GM, Locatelli F, Di Giannatale A. Di Paolo V, et al. Among authors: alaggio r. J Exp Clin Cancer Res. 2024 Oct 9;43(1):282. doi: 10.1186/s13046-024-03197-3. J Exp Clin Cancer Res. 2024. PMID: 39385294 Free PMC article.
Clinicopathological Analysis of a European Cohort of MYOD1 Mutant Rhabdomyosarcomas in Children and Young Adults.
Chisholm JC, Selfe JL, Alaggio R, Cheesman E, Zin A, Tombolan L, Parafioriti A, Milano GM, Adams M, Popov S, Česen M, Tafjord S, Jenney M, Proszek PZ, Schlecht H, Carlo DD, Shipley J, Kelsey A. Chisholm JC, et al. Among authors: alaggio r. Pediatr Blood Cancer. 2025 Jan;72(1):e31428. doi: 10.1002/pbc.31428. Epub 2024 Nov 7. Pediatr Blood Cancer. 2025. PMID: 39511703
Clinical characteristics and outcomes for children, adolescents and young adults with "CIC-fused" or "BCOR-rearranged" soft tissue sarcomas: A multi-institutional European retrospective analysis.
Sparber-Sauer M, Corradini N, Affinita MC, Milano GM, Pierron G, Carton M, Tirode F, Pissaloux D, Alaggio R, Vokuhl C, Bisogno G, Berlanga P, Ferrari A, Orbach D. Sparber-Sauer M, et al. Among authors: alaggio r. Cancer Med. 2023 Jul;12(13):14346-14359. doi: 10.1002/cam4.6113. Epub 2023 May 22. Cancer Med. 2023. PMID: 37212486 Free PMC article.
291 results