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Page 1
SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition.
Lai X, Lui SKL, Lam HY, Adachi Y, Sim WJ, Vasilevski N, Armstrong NJ, Bridgeman SC, Main NM, Tan TZ, Tirnitz-Parker JEE, Thiery JP, Ebi H, Kumar AP, Eichhorn PJA. Lai X, et al. Among authors: main nm. NPJ Precis Oncol. 2023 Dec 15;7(1):136. doi: 10.1038/s41698-023-00486-6. NPJ Precis Oncol. 2023. PMID: 38102334 Free PMC article.
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential.
Carlessi R, Denisenko E, Boslem E, Köhn-Gaone J, Main N, Abu Bakar NDB, Shirolkar GD, Jones M, Beasley AB, Poppe D, Dwyer BJ, Jackaman C, Tjiam MC, Lister R, Karin M, Fallowfield JA, Kendall TJ, Forbes SJ, Gray ES, Olynyk JK, Yeoh G, Forrest ARR, Ramm GA, Febbraio MA, Tirnitz-Parker JEE. Carlessi R, et al. Cell Genom. 2023 Apr 13;3(5):100301. doi: 10.1016/j.xgen.2023.100301. eCollection 2023 May 10. Cell Genom. 2023. PMID: 37228755 Free PMC article.
Targeting the eicosanoid pathway in hepatocellular carcinoma.
Razdan A, Main NM, Chiu V, Shackel NA, de Souza P, Bryant K, Scott KF. Razdan A, et al. Among authors: main nm. Am J Cancer Res. 2021 Jun 15;11(6):2456-2476. eCollection 2021. Am J Cancer Res. 2021. PMID: 34249410 Free PMC article. Review.
CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury.
Yee C, Main NM, Terry A, Stevanovski I, Maczurek A, Morgan AJ, Calabro S, Potter AJ, Iemma TL, Bowen DG, Ahlenstiel G, Warner FJ, McCaughan GW, McLennan SV, Shackel NA. Yee C, et al. Among authors: main nm. PLoS One. 2019 Jul 10;14(7):e0215557. doi: 10.1371/journal.pone.0215557. eCollection 2019. PLoS One. 2019. PMID: 31291257 Free PMC article.