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321 results

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Page 1
Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.
Rosety I, Zagare A, Saraiva C, Nickels S, Antony P, Almeida C, Glaab E, Halder R, Velychko S, Rauen T, Schöler HR, Bolognin S, Sauter T, Jarazo J, Krüger R, Schwamborn JC. Rosety I, et al. Among authors: scholer hr. NPJ Parkinsons Dis. 2023 Dec 18;9(1):166. doi: 10.1038/s41531-023-00616-8. NPJ Parkinsons Dis. 2023. PMID: 38110400 Free PMC article.
Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors.
Mavrommatis L, Jeong HW, Kindler U, Gomez-Giro G, Kienitz MC, Stehling M, Psathaki OE, Zeuschner D, Bixel MG, Han D, Morosan-Puopolo G, Gerovska D, Yang JH, Kim JB, Arauzo-Bravo MJ, Schwamborn JC, Hahn SA, Adams RH, Schöler HR, Vorgerd M, Brand-Saberi B, Zaehres H. Mavrommatis L, et al. Among authors: scholer hr. Elife. 2023 Nov 14;12:RP87081. doi: 10.7554/eLife.87081. Elife. 2023. PMID: 37963071 Free PMC article.
Highly cooperative chimeric super-SOX induces naive pluripotency across species.
MacCarthy CM, Wu G, Malik V, Menuchin-Lasowski Y, Velychko T, Keshet G, Fan R, Bedzhov I, Church GM, Jauch R, Cojocaru V, Schöler HR, Velychko S. MacCarthy CM, et al. Among authors: scholer hr. Cell Stem Cell. 2024 Jan 4;31(1):127-147.e9. doi: 10.1016/j.stem.2023.11.010. Epub 2023 Dec 22. Cell Stem Cell. 2024. PMID: 38141611 Free article.
Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate.
Schaefer T, Mittal N, Wang H, Ataman M, Candido S, Lötscher J, Velychko S, Tintignac L, Bock T, Börsch A, Baßler J, Rao TN, Zmajkovic J, Roffeis S, Löliger J, Jacob F, Dumlin A, Schürch C, Schmidt A, Skoda RC, Wymann MP, Hess C, Schöler HR, Zaehres H, Hurt E, Zavolan M, Lengerke C. Schaefer T, et al. Among authors: scholer hr. Cell Rep. 2024 Oct 22;43(10):114807. doi: 10.1016/j.celrep.2024.114807. Epub 2024 Oct 3. Cell Rep. 2024. PMID: 39368083 Free article.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Al-Dalahmah O, Lam M, McInvale JJ, Qu W, Nguyen T, Mun JY, Kwon S, Ifediora N, Mahajan A, Humala N, Winters T, Angeles E, Jakubiak KA, Kühn R, Kim YA, De Rosa MC, Doege CA, Paryani F, Flowers X, Dovas A, Mela A, Lu H, DeTure MA, Vonsattel JP, Wszolek ZK, Dickson DW, Kuhlmann T, Zaehres H, Schöler HR, Sproul AA, Siegelin MD, De Jager PL, Goldman JE, Menon V, Canoll P, Hargus G. Al-Dalahmah O, et al. Among authors: scholer hr. Cell Stem Cell. 2024 May 2;31(5):676-693.e10. doi: 10.1016/j.stem.2024.03.013. Epub 2024 Apr 15. Cell Stem Cell. 2024. PMID: 38626772 Free article.
Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells.
Xu G, Fatima A, Breitbach M, Kuzmenkin A, Fügemann CJ, Ivanyuk D, Kim KP, Cantz T, Pfannkuche K, Schöler HR, Fleischmann BK, Hescheler J, Šarić T. Xu G, et al. Among authors: scholer hr. Int J Mol Sci. 2023 Mar 31;24(7):6546. doi: 10.3390/ijms24076546. Int J Mol Sci. 2023. PMID: 37047520 Free PMC article.
Inhibition of BET selectively eliminates undifferentiated pluripotent stem cells.
Im JH, Hwang SI, Kim JW, Park SJ, Kang KR, You JS, Kim KP, Moon SH, Cha HJ, Chung HM, Schöler HR, Hyun JK, Han DW. Im JH, et al. Among authors: scholer hr. Sci Bull (Beijing). 2018 Apr 30;63(8):477-487. doi: 10.1016/j.scib.2018.02.023. Epub 2018 Mar 15. Sci Bull (Beijing). 2018. PMID: 36658808
MAPT genotype-dependent mitochondrial aberration and ROS production trigger dysfunction and death in cortical neurons of patients with hereditary FTLD.
Korn L, Speicher AM, Schroeter CB, Gola L, Kaehne T, Engler A, Disse P, Fernández-Orth J, Csatári J, Naumann M, Seebohm G, Meuth SG, Schöler HR, Wiendl H, Kovac S, Pawlowski M. Korn L, et al. Among authors: scholer hr. Redox Biol. 2023 Feb;59:102597. doi: 10.1016/j.redox.2022.102597. Epub 2022 Dec 30. Redox Biol. 2023. PMID: 36599286 Free PMC article.
Author Correction: Changing the public perception of human embryology.
Rivron NC, Martinez-Arias A, Sermon K, Mummery C, Schöler HR, Wells J, Nichols J, Hadjantonakis AK, Lancaster MA, Moris N, Fu J, Sturmey RG, Niakan K, Rossant J, Kato K. Rivron NC, et al. Among authors: scholer hr. Nat Cell Biol. 2023 Dec;25(12):1884. doi: 10.1038/s41556-023-01319-1. Nat Cell Biol. 2023. PMID: 38012405 No abstract available.
321 results