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m6A-mRNA methylation regulates cardiac gene expression and cellular growth.
Kmietczyk V, Riechert E, Kalinski L, Boileau E, Malovrh E, Malone B, Gorska A, Hofmann C, Varma E, Jürgensen L, Kamuf-Schenk V, Altmüller J, Tappu R, Busch M, Most P, Katus HA, Dieterich C, Völkers M. Kmietczyk V, et al. Among authors: hofmann c. Life Sci Alliance. 2019 Apr 9;2(2):e201800233. doi: 10.26508/lsa.201800233. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30967445 Free PMC article.
Monitoring Cell-Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress.
Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Friedrich UA, Mauz V, Backs J, Kramer G, Katus HA, Dieterich C, Völkers M. Doroudgar S, et al. Among authors: hofmann c. Circ Res. 2019 Aug 2;125(4):431-448. doi: 10.1161/CIRCRESAHA.119.314817. Epub 2019 Jul 9. Circ Res. 2019. PMID: 31284834 Free PMC article.
Saraf-dependent activation of mTORC1 regulates cardiac growth.
Sanlialp A, Schumacher D, Kiper L, Varma E, Riechert E, Ho TC, Hofmann C, Kmietczyk V, Zimmermann F, Dlugosz S, Wirth A, Gorska AA, Burghaus J, Camacho Londoño JE, Katus HA, Doroudgar S, Freichel M, Völkers M. Sanlialp A, et al. Among authors: hofmann c. J Mol Cell Cardiol. 2020 Apr;141:30-42. doi: 10.1016/j.yjmcc.2020.03.004. Epub 2020 Mar 13. J Mol Cell Cardiol. 2020. PMID: 32173353
Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.
Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Gür K, Ölschläger J, Kühl F, Martin J, Ramirez-Pedraza M, Fernandez M, Doroudgar S, Méndez R, Katus HA, Hentze MW, Völkers M. Riechert E, et al. Among authors: hofmann c. Cell Rep. 2021 May 11;35(6):109100. doi: 10.1016/j.celrep.2021.109100. Cell Rep. 2021. PMID: 33979607 Free article.
Muscle-specific Cand2 is translationally upregulated by mTORC1 and promotes adverse cardiac remodeling.
Górska AA, Sandmann C, Riechert E, Hofmann C, Malovrh E, Varma E, Kmietczyk V, Ölschläger J, Jürgensen L, Kamuf-Schenk V, Stroh C, Furkel J, Konstandin MH, Sticht C, Boileau E, Dieterich C, Frey N, Katus HA, Doroudgar S, Völkers M. Górska AA, et al. Among authors: hofmann c. EMBO Rep. 2021 Dec 6;22(12):e52170. doi: 10.15252/embr.202052170. Epub 2021 Oct 4. EMBO Rep. 2021. PMID: 34605609 Free PMC article.
Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo.
Varma E, Burghaus J, Schwarzl T, Sekaran T, Gupta P, Górska AA, Hofmann C, Stroh C, Jürgensen L, Kamuf-Schenk V, Li X, Medert R, Leuschner F, Kmietczyk V, Freichel M, Katus HA, Hentze MW, Frey N, Völkers M. Varma E, et al. Among authors: hofmann c. Basic Res Cardiol. 2023 Jun 28;118(1):25. doi: 10.1007/s00395-023-00996-1. Basic Res Cardiol. 2023. PMID: 37378715 Free PMC article.
ATF6 protects against protein misfolding during cardiac hypertrophy.
Hofmann C, Aghajani M, Alcock CD, Blackwood EA, Sandmann C, Herzog N, Groß J, Plate L, Wiseman RL, Kaufman RJ, Katus HA, Jakobi T, Völkers M, Glembotski CC, Doroudgar S. Hofmann C, et al. J Mol Cell Cardiol. 2024 Apr;189:12-24. doi: 10.1016/j.yjmcc.2024.02.001. Epub 2024 Feb 23. J Mol Cell Cardiol. 2024. PMID: 38401179
656 results