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Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR.
Zong D, Koussa NC, Cornwell JA, Pankajam AV, Kruhlak MJ, Wong N, Chari R, Cappell SD, Nussenzweig A. Zong D, et al. Among authors: cappell sd. bioRxiv [Preprint]. 2023 Jul 30:2023.07.28.550976. doi: 10.1101/2023.07.28.550976. bioRxiv. 2023. Update in: Genes Dev. 2023 Oct 1;37(19-20):913-928. doi: 10.1101/gad.351085.123 PMID: 37662356 Free PMC article. Updated. Preprint.
Lineage-specific CDK activity dynamics characterize early mammalian development.
Saykali B, Tran AD, Cornwell JA, Caldwell MA, Sangsari PR, Morgan NY, Kruhlak MJ, Cappell SD, Ruiz S. Saykali B, et al. Among authors: cappell sd. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.599098. doi: 10.1101/2024.06.14.599098. bioRxiv. 2024. PMID: 39372752 Free PMC article. Preprint.
Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.
Funk AL, Katerji M, Afifi M, Nyswaner K, Woodroofe CC, Edwards ZC, Lindberg E, Bergman KL, Gough NR, Rubin MR, Karpińska K, Trotter EW, Dash S, Ries AL, James A, Robinson CM, Difilippantonio S, Karim BO, Chang TC, Chen L, Xu X, Doroshow JH, Ahel I, Marusiak AA, Swenson RE, Cappell SD, Brognard J. Funk AL, et al. Among authors: cappell sd. bioRxiv [Preprint]. 2024 Nov 20:2024.11.19.623840. doi: 10.1101/2024.11.19.623840. bioRxiv. 2024. PMID: 39605563 Free PMC article. Preprint.
Loss of CDK4/6 activity in S/G2 phase leads to cell cycle reversal.
Cornwell JA, Crncec A, Afifi MM, Tang K, Amin R, Cappell SD. Cornwell JA, et al. Among authors: cappell sd. Nature. 2023 Jul;619(7969):363-370. doi: 10.1038/s41586-023-06274-3. Epub 2023 Jul 5. Nature. 2023. PMID: 37407814 Free PMC article.
25 results