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Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Ung J, et al. Among authors: chalfant ce. bioRxiv [Preprint]. 2023 Oct 23:2023.10.21.563437. doi: 10.1101/2023.10.21.563437. bioRxiv. 2023. Update in: Cancers (Basel). 2023 Dec 15;15(24):5866. doi: 10.3390/cancers15245866. PMID: 37961314 Free PMC article. Updated. Preprint.
Acute myeloid leukemia mitochondria hydrolyze ATP to resist chemotherapy.
Hagen JT, Montgomery M, Aruleba R, Chrest B, Green TD, Kassai M, Zeczycki T, Schmidt CA, Bhowmick D, Tan SF, Feith D, Chalfant C, Loughran T, Liles D, Minden M, Schimmer A, Cabot M, McClung J, Fisher-Wellman K. Hagen JT, et al. bioRxiv [Preprint]. 2024 Nov 11:2024.04.12.589110. doi: 10.1101/2024.04.12.589110. bioRxiv. 2024. PMID: 38659944 Free PMC article. Preprint.
144 results