Lien YTK - Search Results

1

UGT1A4 Polymorphism is not Associated with a Clinically Relevant Change in Giredestrant Exposure.

Malhi V, Nowicka M, Chen YC, Agarwal P, Waldvogel M, Lien YTK, Hafner M, Perez-Moreno P, Moore HM, Yu J. Malhi V, et al. Among authors: lien ytk. Cancer Chemother Pharmacol. 2024 Jul;94(1):117-122. doi: 10.1007/s00280-023-04634-4. Epub 2024 Feb 2. Cancer Chemother Pharmacol. 2024. PMID: 38305868 Free PMC article.

2

Applications of Advanced Natural Language Processing for Clinical Pharmacology.

Hsu JC, Wu M, Kim C, Vora B, Lien YTK, Jindal A, Yoshida K, Kawakatsu S, Gore J, Jin JY, Lu C, Chen B, Wu B. Hsu JC, et al. Among authors: lien ytk. Clin Pharmacol Ther. 2024 Apr;115(4):786-794. doi: 10.1002/cpt.3161. Epub 2024 Jan 24. Clin Pharmacol Ther. 2024. PMID: 38140747

3

Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug-induced heart rate changes.

Brooks L, Dolton M, Langenhorst J, Yoshida K, Lien YTK, Malhi V, Li C, Perez-Moreno P, Bond J, Chen YC, Yu J. Brooks L, et al. Among authors: lien ytk. Clin Transl Sci. 2023 May;16(5):823-834. doi: 10.1111/cts.13491. Epub 2023 Feb 22. Clin Transl Sci. 2023. PMID: 36772881 Free PMC article.

4

The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies.

Pressly MA, Peletier LA, Zheng S, Sharma VD, Lien YTK, Wang W, Zhou H, Schmidt S. Pressly MA, et al. Among authors: lien ytk. CPT Pharmacometrics Syst Pharmacol. 2023 May;12(5):639-655. doi: 10.1002/psp4.12927. Epub 2023 Mar 23. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36752286 Free PMC article.

5

From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology Modeling in Cancer Immunotherapy.

Lemaire V, Bassen D, Reed M, Song R, Khalili S, Lien YTK, Huang L, Singh AP, Stamatelos S, Bottino D, Hua F. Lemaire V, et al. Among authors: lien ytk. Clin Pharmacol Ther. 2023 May;113(5):963-972. doi: 10.1002/cpt.2770. Epub 2022 Nov 10. Clin Pharmacol Ther. 2023. PMID: 36282521 Review.

6

Establishment of a Disease-Drug Trial Model for Postmenopausal Osteoporosis: A Zoledronic Acid Case Study.

Lien YTK, Madrasi K, Samant S, Kim MJ, Li F, Li L, Wang Y, Schmidt S. Lien YTK, et al. J Clin Pharmacol. 2020 Dec;60 Suppl 2:S86-S102. doi: 10.1002/jcph.1748. J Clin Pharmacol. 2020. PMID: 33274518

7

Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim.

Basu S, Lien YTK, Vozmediano V, Schlender JF, Eissing T, Schmidt S, Niederalt C. Basu S, et al. Among authors: lien ytk. Front Pharmacol. 2020 Jun 11;11:868. doi: 10.3389/fphar.2020.00868. eCollection 2020. Front Pharmacol. 2020. PMID: 32595502 Free PMC article.

8

Vancomycin in peritoneal dialysis: Clinical pharmacology considerations in therapy.

Lam E, Lien YTK, Kraft WK, Piraino B, Vozmediano V, Schmidt S, Zhang J. Lam E, et al. Among authors: lien ytk. Perit Dial Int. 2020 Jul;40(4):384-393. doi: 10.1177/0896860819889774. Epub 2020 Feb 17. Perit Dial Int. 2020. PMID: 32065053 Free PMC article. Review.

9

Identification of new oral dosing regimens for the neuraminidase inhibitor oseltamivir in patients with moderate and severe renal impairment.

Kamal MA, Brennan BJ, Subramoney V, Lien YT, Morcos PN, Frey N, Rayner CR. Kamal MA, et al. Clin Pharmacol Drug Dev. 2015 Sep;4(5):326-36. doi: 10.1002/cpdd.203. Epub 2015 Jul 2. Clin Pharmacol Drug Dev. 2015. PMID: 27137141

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