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Tissue factor binds to and inhibits interferon-α receptor 1 signaling.
Manoharan J, Rana R, Kuenze G, Gupta D, Elwakiel A, Ambreen S, Wang H, Banerjee K, Zimmermann S, Singh K, Gupta A, Fatima S, Kretschmer S, Schaefer L, Zeng-Brouwers J, Schwab C, Al-Dabet MM, Gadi I, Altmann H, Koch T, Poitz DM, Baber R, Kohli S, Shahzad K, Geffers R, Lee-Kirsch MA, Kalinke U, Meiler J, Mackman N, Isermann B. Manoharan J, et al. Among authors: wang h. Immunity. 2024 Jan 9;57(1):68-85.e11. doi: 10.1016/j.immuni.2023.11.017. Epub 2023 Dec 22. Immunity. 2024. PMID: 38141610
Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability.
Seehaus S, Shahzad K, Kashif M, Vinnikov IA, Schiller M, Wang H, Madhusudhan T, Eckstein V, Bierhaus A, Bea F, Blessing E, Weiler H, Frommhold D, Nawroth PP, Isermann B. Seehaus S, et al. Among authors: wang h. Circulation. 2009 Sep 1;120(9):774-84. doi: 10.1161/CIRCULATIONAHA.109.849539. Epub 2009 Aug 17. Circulation. 2009. PMID: 19687358
Minocycline reduces plaque size in diet induced atherosclerosis via p27(Kip1).
Shahzad K, Thati M, Wang H, Kashif M, Wolter J, Ranjan S, He T, Zhou Q, Blessing E, Bierhaus A, Nawroth PP, Isermann B. Shahzad K, et al. Among authors: wang h. Atherosclerosis. 2011 Nov;219(1):74-83. doi: 10.1016/j.atherosclerosis.2011.05.041. Epub 2011 Jun 13. Atherosclerosis. 2011. PMID: 21719015
Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes.
Madhusudhan T, Wang H, Straub BK, Gröne E, Zhou Q, Shahzad K, Müller-Krebs S, Schwenger V, Gerlitz B, Grinnell BW, Griffin JH, Reiser J, Gröne HJ, Esmon CT, Nawroth PP, Isermann B. Madhusudhan T, et al. Among authors: wang h. Blood. 2012 Jan 19;119(3):874-83. doi: 10.1182/blood-2011-07-365973. Epub 2011 Nov 23. Blood. 2012. PMID: 22117049 Free PMC article.
Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation.
Kashif M, Hellwig A, Hashemolhosseini S, Kumar V, Bock F, Wang H, Shahzad K, Ranjan S, Wolter J, Madhusudhan T, Bierhaus A, Nawroth P, Isermann B. Kashif M, et al. Among authors: wang h. J Biol Chem. 2012 Feb 17;287(8):5400-11. doi: 10.1074/jbc.M111.289801. Epub 2011 Dec 15. J Biol Chem. 2012. PMID: 22174410 Free PMC article.
Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc.
Bock F, Shahzad K, Wang H, Stoyanov S, Wolter J, Dong W, Pelicci PG, Kashif M, Ranjan S, Schmidt S, Ritzel R, Schwenger V, Reymann KG, Esmon CT, Madhusudhan T, Nawroth PP, Isermann B. Bock F, et al. Among authors: wang h. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):648-53. doi: 10.1073/pnas.1218667110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267072 Free PMC article.
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