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The HLA-B*57:01 allele corresponds to a very large MHC haploblock likely explaining its massive effect for HIV-1 elite control.
Rahmouni M, De Marco L, Spadoni JL, Tison M, Medina-Santos R, Labib T, Noirel J, Tamouza R, Limou S, Delaneau O, Fellay J, Bensussan A, Le Clerc S, McLaren PJ, Zagury JF. Rahmouni M, et al. Among authors: fellay j. Front Immunol. 2023 Dec 11;14:1305856. doi: 10.3389/fimmu.2023.1305856. eCollection 2023. Front Immunol. 2023. PMID: 38146367 Free PMC article.
Human Genomics of COVID-19 Pneumonia: Contributions of Rare and Common Variants.
Cobat A, Zhang Q; COVID Human Genetic Effort; Abel L, Casanova JL, Fellay J. Cobat A, et al. Among authors: fellay j. Annu Rev Biomed Data Sci. 2023 Aug 10;6:465-486. doi: 10.1146/annurev-biodatasci-020222-021705. Epub 2023 May 17. Annu Rev Biomed Data Sci. 2023. PMID: 37196358 Free PMC article. Review.
Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons.
Rotger M, Glass TR, Junier T, Lundgren J, Neaton JD, Poloni ES, van 't Wout AB, Lubomirov R, Colombo S, Martinez R, Rauch A, Günthard HF, Neuhaus J, Wentworth D, van Manen D, Gras LA, Schuitemaker H, Albini L, Torti C, Jacobson LP, Li X, Kingsley LA, Carli F, Guaraldi G, Ford ES, Sereti I, Hadigan C, Martinez E, Arnedo M, Egaña-Gorroño L, Gatell JM, Law M, Bendall C, Petoumenos K, Rockstroh J, Wasmuth JC, Kabamba K, Delforge M, De Wit S, Berger F, Mauss S, de Paz Sierra M, Losso M, Belloso WH, Leyes M, Campins A, Mondi A, De Luca A, Bernardino I, Barriuso-Iglesias M, Torrecilla-Rodriguez A, Gonzalez-Garcia J, Arribas JR, Fanti I, Gel S, Puig J, Negredo E, Gutierrez M, Domingo P, Fischer J, Fätkenheuer G, Alonso-Villaverde C, Macken A, Woo J, McGinty T, Mallon P, Mangili A, Skinner S, Wanke CA, Reiss P, Weber R, Bucher HC, Fellay J, Telenti A, Tarr PE; MAGNIFICENT Consortium; INSIGHT; Swiss HIV Cohort Study. Rotger M, et al. Among authors: fellay j. Clin Infect Dis. 2013 Jul;57(1):112-21. doi: 10.1093/cid/cit196. Epub 2013 Mar 26. Clin Infect Dis. 2013. PMID: 23532479 Free PMC article.
Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study.
Schwenke JM, Thorball CW, Schoepf IC, Ryom L, Hasse B, Lamy O, Calmy A, Wandeler G, Marzolini C, Kahlert CR, Bernasconi E, Kouyos RD, Günthard HF, Ledergerber B, Fellay J, Burkhalter F, Tarr PE; Swiss HIV Cohort Study. Schwenke JM, et al. Among authors: fellay j. J Infect Dis. 2023 Sep 15;228(6):742-750. doi: 10.1093/infdis/jiad179. J Infect Dis. 2023. PMID: 37225667 Free PMC article.
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.
Marchal A, Cirulli ET, Neveux I, Bellos E, Thwaites RS, Schiabor Barrett KM, Zhang Y, Nemes-Bokun I, Kalinova M, Catchpole A, Tangye SG, Spaan AN, Lack JB, Ghosn J, Burdet C, Gorochov G, Tubach F, Hausfater P; COVID Human Genetic Effort; COVIDeF Study Group; French COVID Cohort Study Group; CoV-Contact Cohort; COVID-STORM Clinicians; COVID Clinicians; Orchestra Working Group; Amsterdam UMC COVID-19 Biobank; NIAID-USUHS COVID Study Group; Dalgard CL, Zhang SY, Zhang Q, Chiu C, Fellay J, Grzymski JJ, Sancho-Shimizu V, Abel L, Casanova JL, Cobat A, Bolze A. Marchal A, et al. Among authors: fellay j. HGG Adv. 2024 Jul 18;5(3):100300. doi: 10.1016/j.xhgg.2024.100300. Epub 2024 Apr 26. HGG Adv. 2024. PMID: 38678364 Free PMC article.
Epistatic interaction between ERAP2 and HLA modulates HIV-1 adaptation and disease outcome in an Australian population.
Al-Kaabi M, Deshpande P, Firth M, Pavlos R, Chopra A, Basiri H, Currenti J, Alves E, Kalams S, Fellay J, Phillips E, Mallal S, John M, Gaudieri S. Al-Kaabi M, et al. Among authors: fellay j. PLoS Pathog. 2024 Jul 9;20(7):e1012359. doi: 10.1371/journal.ppat.1012359. eCollection 2024 Jul. PLoS Pathog. 2024. PMID: 38980912 Free PMC article.
Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort.
Dos Santos Q, Leung P, Thorball CW, Ledergerber B, Fellay J, MacPherson CR, Hornum M, Terrones-Campos C, Rasmussen A, Gustafsson F, Perch M, Sørensen SS, Ekenberg C, Lundgren JD, Feldt-Rasmussen B, Reekie J. Dos Santos Q, et al. Among authors: fellay j. Front Mol Biosci. 2023 Dec 7;10:1282412. doi: 10.3389/fmolb.2023.1282412. eCollection 2023. Front Mol Biosci. 2023. PMID: 38131015 Free PMC article.
Self-reported neurocognitive complaints in the Swiss HIV Cohort Study: a viral genome-wide association study.
Zeeb M, Pasin C, Cavassini M, Bieler-Aeschlimann M, Frischknecht P, Kusejko K, Fellay J, Blanquart F, Metzner KJ, Neumann K, Jörimann L, Tschumi J, Bernasconi E, Huber M, Kovari H, Leuzinger K, Notter J, Perreau M, Rauch A, Ramette A, Stöckle M, Yerly S, Günthard HF, Kouyos RD; Swiss HIV Cohort Study. Zeeb M, et al. Among authors: fellay j. Brain Commun. 2024 May 31;6(4):fcae188. doi: 10.1093/braincomms/fcae188. eCollection 2024. Brain Commun. 2024. PMID: 38961872 Free PMC article.
426 results